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Lamin-B1 is a senescence-associated biomarker in clear-cell renal cell carcinoma

Clear-cell renal cell carcinoma (ccRCC) is a von-Hippel-Lindau gene (VHL) associated tumor disease. In addition to activating the hypoxia inducible factor (HIF) dependent oxygen-sensing pathway, VHL loss also has an impact on a HIF-independent senescence program which functions as a tumorigenesis ba...

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Detalles Bibliográficos
Autores principales: Radspieler, Melissa Marie, Schindeldecker, Mario, Stenzel, Philipp, Försch, Sebastian, Tagscherer, Katrin E., Herpel, Esther, Hohenfellner, Markus, Hatiboglu, Gencay, Roth, Wilfried, Macher-Goeppinger, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676677/
https://www.ncbi.nlm.nih.gov/pubmed/31402955
http://dx.doi.org/10.3892/ol.2019.10593

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