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Lamin-B1 is a senescence-associated biomarker in clear-cell renal cell carcinoma
Clear-cell renal cell carcinoma (ccRCC) is a von-Hippel-Lindau gene (VHL) associated tumor disease. In addition to activating the hypoxia inducible factor (HIF) dependent oxygen-sensing pathway, VHL loss also has an impact on a HIF-independent senescence program which functions as a tumorigenesis ba...
Autores principales: | Radspieler, Melissa Marie, Schindeldecker, Mario, Stenzel, Philipp, Försch, Sebastian, Tagscherer, Katrin E., Herpel, Esther, Hohenfellner, Markus, Hatiboglu, Gencay, Roth, Wilfried, Macher-Goeppinger, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676677/ https://www.ncbi.nlm.nih.gov/pubmed/31402955 http://dx.doi.org/10.3892/ol.2019.10593 |
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