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Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer

Diagnostic value of fine-needle aspiration (FNA) combined with ultrasound for thyroid cancer was evaluated. A retrospective analysis was performed on the preoperative FNA and ultrasound data of 165 thyroid nodule patients, were divided into group A (≤1 cm group) and group B (>1 cm group) based on...

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Autores principales: Li, Juan, Wang, Qian, Wang, Liangliang, Wang, Jing, Wang, Dongxiao, Xin, Zhaoqin, Liu, Yilin, Zhao, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676711/
https://www.ncbi.nlm.nih.gov/pubmed/31402937
http://dx.doi.org/10.3892/ol.2019.10584
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author Li, Juan
Wang, Qian
Wang, Liangliang
Wang, Jing
Wang, Dongxiao
Xin, Zhaoqin
Liu, Yilin
Zhao, Qinghua
author_facet Li, Juan
Wang, Qian
Wang, Liangliang
Wang, Jing
Wang, Dongxiao
Xin, Zhaoqin
Liu, Yilin
Zhao, Qinghua
author_sort Li, Juan
collection PubMed
description Diagnostic value of fine-needle aspiration (FNA) combined with ultrasound for thyroid cancer was evaluated. A retrospective analysis was performed on the preoperative FNA and ultrasound data of 165 thyroid nodule patients, were divided into group A (≤1 cm group) and group B (>1 cm group) based on the maximum diameter line of the thyroid nodule. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA, ultrasound and FNA combined with ultrasound in the diagnosis of thyroid cancer were analyzed and compared. In group A (≤1 cm group), the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 93.33, 71.43, 91.04, 96.55 and 55.56%, respectively, those of ultrasound were 86.67, 28.57, 80.60, 91.23 and 20%, respectively, and those of FNA combined with ultrasound were 100, 28.57, 92.54, 92.6 and 100%, respectively, with statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P<0.05). In group B, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 100, 54.55, 94.90, 94.57 and 100%, respectively, those of ultrasound were 96.55, 72.73, 93.88, 96.55 and 72.73%, respectively, and those of FNA combined with ultrasound were 100, 63.64, 97.96, 95.92 and 100%, respectively, without statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P>0.05). FNA combined with ultrasound significantly improved the sensitivity and accuracy in the diagnosis of the thyroid nodule in group A, but it did not significantly improve the accuracy, sensitivity and specificity in the diagnosis of the thyroid nodule in group B.
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spelling pubmed-66767112019-08-09 Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer Li, Juan Wang, Qian Wang, Liangliang Wang, Jing Wang, Dongxiao Xin, Zhaoqin Liu, Yilin Zhao, Qinghua Oncol Lett Articles Diagnostic value of fine-needle aspiration (FNA) combined with ultrasound for thyroid cancer was evaluated. A retrospective analysis was performed on the preoperative FNA and ultrasound data of 165 thyroid nodule patients, were divided into group A (≤1 cm group) and group B (>1 cm group) based on the maximum diameter line of the thyroid nodule. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA, ultrasound and FNA combined with ultrasound in the diagnosis of thyroid cancer were analyzed and compared. In group A (≤1 cm group), the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 93.33, 71.43, 91.04, 96.55 and 55.56%, respectively, those of ultrasound were 86.67, 28.57, 80.60, 91.23 and 20%, respectively, and those of FNA combined with ultrasound were 100, 28.57, 92.54, 92.6 and 100%, respectively, with statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P<0.05). In group B, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 100, 54.55, 94.90, 94.57 and 100%, respectively, those of ultrasound were 96.55, 72.73, 93.88, 96.55 and 72.73%, respectively, and those of FNA combined with ultrasound were 100, 63.64, 97.96, 95.92 and 100%, respectively, without statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P>0.05). FNA combined with ultrasound significantly improved the sensitivity and accuracy in the diagnosis of the thyroid nodule in group A, but it did not significantly improve the accuracy, sensitivity and specificity in the diagnosis of the thyroid nodule in group B. D.A. Spandidos 2019-09 2019-07-05 /pmc/articles/PMC6676711/ /pubmed/31402937 http://dx.doi.org/10.3892/ol.2019.10584 Text en Copyright: © Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Li, Juan
Wang, Qian
Wang, Liangliang
Wang, Jing
Wang, Dongxiao
Xin, Zhaoqin
Liu, Yilin
Zhao, Qinghua
Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer
title Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer
title_full Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer
title_fullStr Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer
title_full_unstemmed Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer
title_short Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer
title_sort diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676711/
https://www.ncbi.nlm.nih.gov/pubmed/31402937
http://dx.doi.org/10.3892/ol.2019.10584
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