Cargando…
Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer
Diagnostic value of fine-needle aspiration (FNA) combined with ultrasound for thyroid cancer was evaluated. A retrospective analysis was performed on the preoperative FNA and ultrasound data of 165 thyroid nodule patients, were divided into group A (≤1 cm group) and group B (>1 cm group) based on...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676711/ https://www.ncbi.nlm.nih.gov/pubmed/31402937 http://dx.doi.org/10.3892/ol.2019.10584 |
_version_ | 1783440818997035008 |
---|---|
author | Li, Juan Wang, Qian Wang, Liangliang Wang, Jing Wang, Dongxiao Xin, Zhaoqin Liu, Yilin Zhao, Qinghua |
author_facet | Li, Juan Wang, Qian Wang, Liangliang Wang, Jing Wang, Dongxiao Xin, Zhaoqin Liu, Yilin Zhao, Qinghua |
author_sort | Li, Juan |
collection | PubMed |
description | Diagnostic value of fine-needle aspiration (FNA) combined with ultrasound for thyroid cancer was evaluated. A retrospective analysis was performed on the preoperative FNA and ultrasound data of 165 thyroid nodule patients, were divided into group A (≤1 cm group) and group B (>1 cm group) based on the maximum diameter line of the thyroid nodule. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA, ultrasound and FNA combined with ultrasound in the diagnosis of thyroid cancer were analyzed and compared. In group A (≤1 cm group), the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 93.33, 71.43, 91.04, 96.55 and 55.56%, respectively, those of ultrasound were 86.67, 28.57, 80.60, 91.23 and 20%, respectively, and those of FNA combined with ultrasound were 100, 28.57, 92.54, 92.6 and 100%, respectively, with statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P<0.05). In group B, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 100, 54.55, 94.90, 94.57 and 100%, respectively, those of ultrasound were 96.55, 72.73, 93.88, 96.55 and 72.73%, respectively, and those of FNA combined with ultrasound were 100, 63.64, 97.96, 95.92 and 100%, respectively, without statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P>0.05). FNA combined with ultrasound significantly improved the sensitivity and accuracy in the diagnosis of the thyroid nodule in group A, but it did not significantly improve the accuracy, sensitivity and specificity in the diagnosis of the thyroid nodule in group B. |
format | Online Article Text |
id | pubmed-6676711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-66767112019-08-09 Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer Li, Juan Wang, Qian Wang, Liangliang Wang, Jing Wang, Dongxiao Xin, Zhaoqin Liu, Yilin Zhao, Qinghua Oncol Lett Articles Diagnostic value of fine-needle aspiration (FNA) combined with ultrasound for thyroid cancer was evaluated. A retrospective analysis was performed on the preoperative FNA and ultrasound data of 165 thyroid nodule patients, were divided into group A (≤1 cm group) and group B (>1 cm group) based on the maximum diameter line of the thyroid nodule. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA, ultrasound and FNA combined with ultrasound in the diagnosis of thyroid cancer were analyzed and compared. In group A (≤1 cm group), the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 93.33, 71.43, 91.04, 96.55 and 55.56%, respectively, those of ultrasound were 86.67, 28.57, 80.60, 91.23 and 20%, respectively, and those of FNA combined with ultrasound were 100, 28.57, 92.54, 92.6 and 100%, respectively, with statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P<0.05). In group B, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of FNA in the diagnosis of thyroid cancer were 100, 54.55, 94.90, 94.57 and 100%, respectively, those of ultrasound were 96.55, 72.73, 93.88, 96.55 and 72.73%, respectively, and those of FNA combined with ultrasound were 100, 63.64, 97.96, 95.92 and 100%, respectively, without statistically significant differences in the sensitivity, specificity, accuracy, positive predictive value and negative predictive value between FNA, ultrasound and FNA combined with ultrasound (P>0.05). FNA combined with ultrasound significantly improved the sensitivity and accuracy in the diagnosis of the thyroid nodule in group A, but it did not significantly improve the accuracy, sensitivity and specificity in the diagnosis of the thyroid nodule in group B. D.A. Spandidos 2019-09 2019-07-05 /pmc/articles/PMC6676711/ /pubmed/31402937 http://dx.doi.org/10.3892/ol.2019.10584 Text en Copyright: © Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Li, Juan Wang, Qian Wang, Liangliang Wang, Jing Wang, Dongxiao Xin, Zhaoqin Liu, Yilin Zhao, Qinghua Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer |
title | Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer |
title_full | Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer |
title_fullStr | Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer |
title_full_unstemmed | Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer |
title_short | Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer |
title_sort | diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676711/ https://www.ncbi.nlm.nih.gov/pubmed/31402937 http://dx.doi.org/10.3892/ol.2019.10584 |
work_keys_str_mv | AT lijuan diagnosticvalueoffineneedleaspirationcombinedwithultrasoundforthyroidcancer AT wangqian diagnosticvalueoffineneedleaspirationcombinedwithultrasoundforthyroidcancer AT wangliangliang diagnosticvalueoffineneedleaspirationcombinedwithultrasoundforthyroidcancer AT wangjing diagnosticvalueoffineneedleaspirationcombinedwithultrasoundforthyroidcancer AT wangdongxiao diagnosticvalueoffineneedleaspirationcombinedwithultrasoundforthyroidcancer AT xinzhaoqin diagnosticvalueoffineneedleaspirationcombinedwithultrasoundforthyroidcancer AT liuyilin diagnosticvalueoffineneedleaspirationcombinedwithultrasoundforthyroidcancer AT zhaoqinghua diagnosticvalueoffineneedleaspirationcombinedwithultrasoundforthyroidcancer |