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Changing profiles of patients undergoing transurethral resection of the prostate over a decade: A single-center experience

CONTEXT: Patients with benign prostatic hyperplasia (BPH) usually form the bulk in urology outpatient departments. The management options include medical therapy or surgery. Transurethral resection of the prostate (TURP) has been the mainstay of surgical management. The use of medical therapy has in...

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Autores principales: Agrawal, Manav, Kumar, Manoj, Pandey, Siddharth, Aggarwal, Ajay, Sankhwar, Satyanarayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676823/
https://www.ncbi.nlm.nih.gov/pubmed/31413505
http://dx.doi.org/10.4103/UA.UA_198_17
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author Agrawal, Manav
Kumar, Manoj
Pandey, Siddharth
Aggarwal, Ajay
Sankhwar, Satyanarayan
author_facet Agrawal, Manav
Kumar, Manoj
Pandey, Siddharth
Aggarwal, Ajay
Sankhwar, Satyanarayan
author_sort Agrawal, Manav
collection PubMed
description CONTEXT: Patients with benign prostatic hyperplasia (BPH) usually form the bulk in urology outpatient departments. The management options include medical therapy or surgery. Transurethral resection of the prostate (TURP) has been the mainstay of surgical management. The use of medical therapy has increased over the years. This has led to a shift in the profiles of patients undergoing surgical management of BPH. AIMS: We conducted this study to analyze the differences in profiles of patients undergoing TURP over a decade. SETTINGS AND DESIGN: This was a retrospective study. SUBJECTS AND METHODS: We retrospectively reviewed the medical records of all patients who underwent TURP from January 1 to December 31 in 2006 and 2016. The age, preexisting comorbidities, prostate volume, operative time, mean prostatic tissue removed, duration of hospitalization, and complications were evaluated among the two groups of patients. Charlson comorbidity index was used to evaluate the preexisting comorbidities, and the modified Clavien classification system was used for evaluating the perioperative and postoperative complications. RESULTS: A total of 114 and 125 patients underwent TURP in 2006 and 2016, respectively. The mean age of the patients was 62.1 ± 8.22 and 66.94 ± 9.12 years in 2006 and 2016, respectively. The serum prostate-specific antigen levels increased from 4.39 ± 4.425 to 5.59 ± 7.61 ng/ml a decade apart. A number of patients taking medical therapy before surgical intervention increased from 62.23% to 75.2% (P < 0.05). There was a significant increase in the mean prostatic volume and weight. There was only a modest increase of 1.94% in the total number of complications (P > 0.05) and no significant change in the rates of complications. CONCLUSIONS: Medical therapy for BPH patients has resulted in delayed surgical interventions. The complication rates have not increased. Thus, the increased use of medical therapy in BPH patients is justified though TURP may still be considered the gold standard.
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spelling pubmed-66768232019-08-14 Changing profiles of patients undergoing transurethral resection of the prostate over a decade: A single-center experience Agrawal, Manav Kumar, Manoj Pandey, Siddharth Aggarwal, Ajay Sankhwar, Satyanarayan Urol Ann Original Article CONTEXT: Patients with benign prostatic hyperplasia (BPH) usually form the bulk in urology outpatient departments. The management options include medical therapy or surgery. Transurethral resection of the prostate (TURP) has been the mainstay of surgical management. The use of medical therapy has increased over the years. This has led to a shift in the profiles of patients undergoing surgical management of BPH. AIMS: We conducted this study to analyze the differences in profiles of patients undergoing TURP over a decade. SETTINGS AND DESIGN: This was a retrospective study. SUBJECTS AND METHODS: We retrospectively reviewed the medical records of all patients who underwent TURP from January 1 to December 31 in 2006 and 2016. The age, preexisting comorbidities, prostate volume, operative time, mean prostatic tissue removed, duration of hospitalization, and complications were evaluated among the two groups of patients. Charlson comorbidity index was used to evaluate the preexisting comorbidities, and the modified Clavien classification system was used for evaluating the perioperative and postoperative complications. RESULTS: A total of 114 and 125 patients underwent TURP in 2006 and 2016, respectively. The mean age of the patients was 62.1 ± 8.22 and 66.94 ± 9.12 years in 2006 and 2016, respectively. The serum prostate-specific antigen levels increased from 4.39 ± 4.425 to 5.59 ± 7.61 ng/ml a decade apart. A number of patients taking medical therapy before surgical intervention increased from 62.23% to 75.2% (P < 0.05). There was a significant increase in the mean prostatic volume and weight. There was only a modest increase of 1.94% in the total number of complications (P > 0.05) and no significant change in the rates of complications. CONCLUSIONS: Medical therapy for BPH patients has resulted in delayed surgical interventions. The complication rates have not increased. Thus, the increased use of medical therapy in BPH patients is justified though TURP may still be considered the gold standard. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6676823/ /pubmed/31413505 http://dx.doi.org/10.4103/UA.UA_198_17 Text en Copyright: © 2019 Urology Annals http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Agrawal, Manav
Kumar, Manoj
Pandey, Siddharth
Aggarwal, Ajay
Sankhwar, Satyanarayan
Changing profiles of patients undergoing transurethral resection of the prostate over a decade: A single-center experience
title Changing profiles of patients undergoing transurethral resection of the prostate over a decade: A single-center experience
title_full Changing profiles of patients undergoing transurethral resection of the prostate over a decade: A single-center experience
title_fullStr Changing profiles of patients undergoing transurethral resection of the prostate over a decade: A single-center experience
title_full_unstemmed Changing profiles of patients undergoing transurethral resection of the prostate over a decade: A single-center experience
title_short Changing profiles of patients undergoing transurethral resection of the prostate over a decade: A single-center experience
title_sort changing profiles of patients undergoing transurethral resection of the prostate over a decade: a single-center experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676823/
https://www.ncbi.nlm.nih.gov/pubmed/31413505
http://dx.doi.org/10.4103/UA.UA_198_17
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