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The ocular surface after simple limbal epithelial transplant (SLET): A high-resolution OCT study of the early postoperative period

Simple limbal epithelial transplantation (SLET) is an emerging technique for treating unilateral limbal stem cell deficiency. We report the high-resolution, anterior segment optical coherence tomography (OCT) features of the first 2 weeks of a patient undergoing SLET for an old acid injury of the ri...

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Autores principales: Ray Chaudhuri, Bhaskar, Bhaduri, Anirban, Sengupta, Manikuntala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677049/
https://www.ncbi.nlm.nih.gov/pubmed/31332139
http://dx.doi.org/10.4103/ijo.IJO_1722_18
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author Ray Chaudhuri, Bhaskar
Bhaduri, Anirban
Sengupta, Manikuntala
author_facet Ray Chaudhuri, Bhaskar
Bhaduri, Anirban
Sengupta, Manikuntala
author_sort Ray Chaudhuri, Bhaskar
collection PubMed
description Simple limbal epithelial transplantation (SLET) is an emerging technique for treating unilateral limbal stem cell deficiency. We report the high-resolution, anterior segment optical coherence tomography (OCT) features of the first 2 weeks of a patient undergoing SLET for an old acid injury of the right eye, repeatedly from postoperative day 1 through day 14. Three out of 11 explants with the subjacent human amniotic membrane (hAM) and the overlaid bandage contact lens were imaged. The hAM was intact and of the same thickness throughout the study period; the sub-hAM space increased from day 3 to 9 and disappeared by day 10; the explants started thinning from day 3 with the fibrin around them starting to decrease from day 2 and completely disappeared by day 4. Epithelialization occurred between day 8 and 14 and proceeded more rapidly towards the limbus than centrally. There was no change of the corneal stromal thickness or reflectivity. This case report uses high-definition, spectral-domain OCT to document the events on the ocular surface after a successful SLET surgery and opens up an avenue to study epithelialization in a convenient and noninvasive manner.
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spelling pubmed-66770492019-08-14 The ocular surface after simple limbal epithelial transplant (SLET): A high-resolution OCT study of the early postoperative period Ray Chaudhuri, Bhaskar Bhaduri, Anirban Sengupta, Manikuntala Indian J Ophthalmol Case Reports Simple limbal epithelial transplantation (SLET) is an emerging technique for treating unilateral limbal stem cell deficiency. We report the high-resolution, anterior segment optical coherence tomography (OCT) features of the first 2 weeks of a patient undergoing SLET for an old acid injury of the right eye, repeatedly from postoperative day 1 through day 14. Three out of 11 explants with the subjacent human amniotic membrane (hAM) and the overlaid bandage contact lens were imaged. The hAM was intact and of the same thickness throughout the study period; the sub-hAM space increased from day 3 to 9 and disappeared by day 10; the explants started thinning from day 3 with the fibrin around them starting to decrease from day 2 and completely disappeared by day 4. Epithelialization occurred between day 8 and 14 and proceeded more rapidly towards the limbus than centrally. There was no change of the corneal stromal thickness or reflectivity. This case report uses high-definition, spectral-domain OCT to document the events on the ocular surface after a successful SLET surgery and opens up an avenue to study epithelialization in a convenient and noninvasive manner. Wolters Kluwer - Medknow 2019-08 /pmc/articles/PMC6677049/ /pubmed/31332139 http://dx.doi.org/10.4103/ijo.IJO_1722_18 Text en Copyright: © 2019 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Ray Chaudhuri, Bhaskar
Bhaduri, Anirban
Sengupta, Manikuntala
The ocular surface after simple limbal epithelial transplant (SLET): A high-resolution OCT study of the early postoperative period
title The ocular surface after simple limbal epithelial transplant (SLET): A high-resolution OCT study of the early postoperative period
title_full The ocular surface after simple limbal epithelial transplant (SLET): A high-resolution OCT study of the early postoperative period
title_fullStr The ocular surface after simple limbal epithelial transplant (SLET): A high-resolution OCT study of the early postoperative period
title_full_unstemmed The ocular surface after simple limbal epithelial transplant (SLET): A high-resolution OCT study of the early postoperative period
title_short The ocular surface after simple limbal epithelial transplant (SLET): A high-resolution OCT study of the early postoperative period
title_sort ocular surface after simple limbal epithelial transplant (slet): a high-resolution oct study of the early postoperative period
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677049/
https://www.ncbi.nlm.nih.gov/pubmed/31332139
http://dx.doi.org/10.4103/ijo.IJO_1722_18
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