Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature

Sweat gland neoplasms are rare adnexal tumors that pose a diagnostic challenge for both, ophthalmologists and pathologists. Endocrine, mucin producing sweat gland carcinoma (EMPSGC), considered to be analogous to the solid papillary mammary carcinoma is one such tumor. It usually affects elderly, is...

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Autores principales: Mulay, Kaustubh, Menon, Vikas, Lahane, Sumeet, Sharma, Mukesh, Honavar, Santosh G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677066/
https://www.ncbi.nlm.nih.gov/pubmed/31332149
http://dx.doi.org/10.4103/ijo.IJO_1745_18
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author Mulay, Kaustubh
Menon, Vikas
Lahane, Sumeet
Sharma, Mukesh
Honavar, Santosh G
author_facet Mulay, Kaustubh
Menon, Vikas
Lahane, Sumeet
Sharma, Mukesh
Honavar, Santosh G
author_sort Mulay, Kaustubh
collection PubMed
description Sweat gland neoplasms are rare adnexal tumors that pose a diagnostic challenge for both, ophthalmologists and pathologists. Endocrine, mucin producing sweat gland carcinoma (EMPSGC), considered to be analogous to the solid papillary mammary carcinoma is one such tumor. It usually affects elderly, is more frequent in women and has a predilection for skin of the eyelid. Although it has an indolent clinical course, EMPSGC is believed to be a precursor of the invasive mucinous carcinoma and has a potential for local recurrence. We report a series of 10 biopsy-proven EMPSGCs with their immunohistochemical features and review the literature.
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spelling pubmed-66770662019-08-14 Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature Mulay, Kaustubh Menon, Vikas Lahane, Sumeet Sharma, Mukesh Honavar, Santosh G Indian J Ophthalmol Case Reports Sweat gland neoplasms are rare adnexal tumors that pose a diagnostic challenge for both, ophthalmologists and pathologists. Endocrine, mucin producing sweat gland carcinoma (EMPSGC), considered to be analogous to the solid papillary mammary carcinoma is one such tumor. It usually affects elderly, is more frequent in women and has a predilection for skin of the eyelid. Although it has an indolent clinical course, EMPSGC is believed to be a precursor of the invasive mucinous carcinoma and has a potential for local recurrence. We report a series of 10 biopsy-proven EMPSGCs with their immunohistochemical features and review the literature. Wolters Kluwer - Medknow 2019-08 /pmc/articles/PMC6677066/ /pubmed/31332149 http://dx.doi.org/10.4103/ijo.IJO_1745_18 Text en Copyright: © 2019 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Mulay, Kaustubh
Menon, Vikas
Lahane, Sumeet
Sharma, Mukesh
Honavar, Santosh G
Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature
title Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature
title_full Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature
title_fullStr Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature
title_full_unstemmed Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature
title_short Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature
title_sort endocrine mucin-producing sweat gland carcinoma (empsgc) of the eyelid: clinicopathologic features, immunohistochemical findings and review of literature
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677066/
https://www.ncbi.nlm.nih.gov/pubmed/31332149
http://dx.doi.org/10.4103/ijo.IJO_1745_18
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