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Exploring induced pluripotency in human fibroblasts via construction, validation, and application of a gene regulatory network
Reprogramming of somatic cells to induced pluripotent stem cells, by overexpressing certain factors referred to as the reprogramming factors, can revolutionize regenerative medicine. To provide a coherent description of induced pluripotency from the gene regulation perspective, we use 35 microarray...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677386/ https://www.ncbi.nlm.nih.gov/pubmed/31374103 http://dx.doi.org/10.1371/journal.pone.0220742 |