Cargando…

A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions

Necrotizing enterocolitis (NEC) is an idiopathic, inflammatory bowel necrosis of premature infants. Clinical studies have linked NEC with antecedent red blood cell (RBC) transfusions, but the underlying mechanisms are unclear. Here we report a neonatal murine model to investigate this association. C...

Descripción completa

Detalles Bibliográficos
Autores principales:	MohanKumar, Krishnan, Namachivayam, Kopperuncholan, Song, Tanjing, Jake Cha, Byeong, Slate, Andrea, Hendrickson, Jeanne E., Pan, Hua, Wickline, Samuel A., Oh, Joo-Yeun, Patel, Rakesh P., He, Ling, Torres, Benjamin A., Maheshwari, Akhil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677753/ https://www.ncbi.nlm.nih.gov/pubmed/31375667 http://dx.doi.org/10.1038/s41467-019-11199-5

Ejemplares similares

Neonatal Mice with Necrotizing Enterocolitis-like Injury Develop Thrombocytopenia despite Increased Megakaryopoiesis
por: Namachivayam, Kopperuncholan, et al.
Publicado: (2017)

Smad7 Interrupts TGF-β Signaling in Intestinal Macrophages and Promotes Inflammatory Activation of these Cells during Necrotizing Enterocolitis
por: MohanKumar, Krishnan, et al.
Publicado: (2016)

Trinitrobenzene Sulfonic Acid-induced Intestinal Injury in Neonatal Mice Activates Transcriptional Networks Similar to those seen in Human Necrotizing Enterocolitis
por: MohanKumar, Krishnan, et al.
Publicado: (2016)

Role of Platelets in Neonatal Necrotizing Enterocolitis
por: Maheshwari, Akhil
Publicado: (2020)

All-Trans Retinoic Acid Induces TGF-β(2) in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2
por: Namachivayam, Kopperuncholan, et al.
Publicado: (2015)

VEGF mRNA and Protein Concentrations in the Developing Human Eye
por: Ma, Irene T., et al.
Publicado: (2015)

Non-coding RNAs in Neonatal Necrotizing Enterocolitis
por: Donda, Keyur, et al.
Publicado: (2022)

The association of severe anemia, red blood cell transfusion and necrotizing enterocolitis in neonates
por: Song, Juan, et al.
Publicado: (2021)

Imaging for Diagnosis and Assessment of Necrotizing Enterocolitis
por: Mishra, Vinayak, et al.
Publicado: (2022)

Incomplete Resection of Necrotic Bowel May Increase Mortality in Infants with Necrotizing Enterocolitis
por: Garg, Parvesh Mohan, et al.
Publicado: (2020)

Intestinal Dysbiosis and Necrotizing Enterocolitis: Assessment for Causality using Bradford-Hill Criteria
por: Fundora, Jennifer B., et al.
Publicado: (2019)

Role of Near-infrared Spectroscopy in the Diagnosis and Assessment of Necrotizing Enterocolitis
por: Mishra, Vinayak, et al.
Publicado: (2022)

Point-of-care Ultrasound to Diagnose and Monitor the Course of Necrotizing Enterocolitis
por: Chetan, Chinmay, et al.
Publicado: (2023)

Intestinal Epithelial Apoptosis initiates Gut Mucosal Injury during Extracorporeal Membrane Oxygenation in the Newborn Piglet
por: MohanKumar, Krishnan, et al.
Publicado: (2013)

The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor
por: Peng, Jinghua, et al.
Publicado: (2022)

Necrotizing Enterocolitis Associated with Congenital Heart Disease—A Review Article
por: Roychaudhuri, Sriya, et al.
Publicado: (2022)

Depth of Bacterial Invasion in Resected Intestinal Tissue Predicts Mortality in Surgical Necrotizing Enterocolitis
por: Remon, Juan I., et al.
Publicado: (2015)

Current Understanding of Transfusion-associated Necrotizing Enterocolitis: Review of Clinical and Experimental Studies and a Call for More Definitive Evidence
por: Khashu, Minesh, et al.
Publicado: (2022)

Clinical Correlates of Cholestasis in Preterm Infants with Surgical Necrotizing Enterocolitis
por: Garg, Parvesh Mohan, et al.
Publicado: (2023)

Necrotizing Enterocolitis
por: Kim, Stephen S., et al.
Publicado: (2006)

Necrotizing enterocolitis
por: Kulkarni, Anjali, et al.
Publicado: (2001)

Necrotizing Enterocolitis
por: Hunter, Catherine J., et al.
Publicado: (2009)

Necrotizing Enterocolitis
por: Sylvester, Karl G., et al.
Publicado: (2012)

Anemia of Prematurity and Cerebral Near-Infrared Spectroscopy: Should transfusion thresholds in preterm infants be revised?
por: Whitehead, Halana V., et al.
Publicado: (2018)

Cytokines Associated with Necrotizing Enterocolitis in Extremely Low Birth Weight Infants
por: Maheshwari, Akhil, et al.
Publicado: (2014)

Intestinal Resection is More Likely to be Effective in Necrotizing Enterocolitis Extending to Colon than in Disease Limited to the Small Intestine
por: Garg, Parvesh M, et al.
Publicado: (2022)

Neonatal Necrotizing Enterocolitis
por: Gharpure, Vivek
Publicado: (2012)

Neonatal Necrotizing Enterocolitis
por: Lahmiti, Saad, et al.
Publicado: (2011)

Epidemiology of Necrotizing Enterocolitis
por: Stoll, Barbara J.
Publicado: (1994)

Necrotizing Enterocolitis and Infection
por: Willoughby, Rodney E., et al.
Publicado: (1994)

Neonatal necrotizing enterocolitis
por: Kliegman, Robert M.
Publicado: (2006)

Surgical Necrotizing Enterocolitis in Extremely Premature Neonates is Associated with Genetic Variations in an Intergenic Region of Chromosome Eight
por: Jilling, Tamas, et al.
Publicado: (2018)

Neonatal Perforated Appendicitis Masquerading as Necrotizing Enterocolitis
por: Tumen, Andrew, et al.
Publicado: (2017)

Stool Calprotectin in Necrotizing Enterocolitis
por: Albanna, Ehab AM, et al.
Publicado: (2014)

Paneth cells and necrotizing enterocolitis
por: Underwood, Mark A.
Publicado: (2012)

Necrotizing enterocolitis: controversies and challenges
por: Zani, Augusto, et al.
Publicado: (2015)

Infectious Causes of Necrotizing Enterocolitis
por: Coggins, Sarah A., et al.
Publicado: (2015)

The epidemiology and pathogenesis of necrotizing enterocolitis
por: Kosloske, Ann M.
Publicado: (1997)

Treatment and prevention of necrotizing enterocolitis
por: Lee, Jane S, et al.
Publicado: (2003)

Models of the pathogenesis of necrotizing enterocolitis
por: Kliegman, Robert M.
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_8fo13h8n4vcbnllu2iuia8c6fr