Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

Immune tolerance to allografts has been pursued for decades as an important goal in transplantation. Administration of apoptotic donor splenocytes effectively induces antigen-specific tolerance to allografts in murine studies. Here we show that two peritransplant infusions of apoptotic donor leukocy...

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Detalles Bibliográficos
Autores principales: Singh, Amar, Ramachandran, Sabarinathan, Graham, Melanie L., Daneshmandi, Saeed, Heller, David, Suarez-Pinzon, Wilma Lucia, Balamurugan, Appakalai N., Ansite, Jeffrey D., Wilhelm, Joshua J., Yang, Amy, Zhang, Ying, Palani, Nagendra P., Abrahante, Juan E., Burlak, Christopher, Miller, Stephen D., Luo, Xunrong, Hering, Bernhard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677762/
https://www.ncbi.nlm.nih.gov/pubmed/31375697
http://dx.doi.org/10.1038/s41467-019-11338-y

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