An immortalized cell line derived from renal erythropoietin-producing (REP) cells demonstrates their potential to transform into myofibroblasts

The erythroid growth factor erythropoietin (Epo) is produced by renal interstitial fibroblasts, called REP (renal Epo-producing) cells, in a hypoxia-inducible manner. In chronic kidney disease (CKD), REP cells lose their Epo-production ability, leading to renal anaemia. Concurrently, REP cells are s...

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Detalles Bibliográficos
Autores principales: Sato, Koji, Hirano, Ikuo, Sekine, Hiroki, Miyauchi, Kenichiro, Nakai, Taku, Kato, Koichiro, Ito, Sadayoshi, Yamamoto, Masayuki, Suzuki, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677766/
https://www.ncbi.nlm.nih.gov/pubmed/31375751
http://dx.doi.org/10.1038/s41598-019-47766-5

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