Cargando…

Increased glucocorticoid receptor activity and proliferation in metastatic colon cancer

Metastasis is regarded as the fatal hallmark for colon cancer, but molecular mechanisms responsible for it have remained poorly defined. Glucocorticoid receptor (GR) within the tumor microenvironment mediates the effects of stress hormones which are used in clinics for their inflammation-modulatory...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Dan, Tian, Miao, Han, Gang, Li, Jin-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677795/ https://www.ncbi.nlm.nih.gov/pubmed/31375708 http://dx.doi.org/10.1038/s41598-019-47696-2

Ejemplares similares

Association of Glucocorticoid Insensitivity with Increased Expression of Glucocorticoid Receptor β
por: Leung, Donald Y.M., et al.
Publicado: (1997)

Glucocorticoid Receptor–Tethered Mineralocorticoid Receptors Increase Glucocorticoid-Induced Transcriptional Responses
por: Rivers, Caroline A, et al.
Publicado: (2019)

Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells
por: Ouyang, N, et al.
Publicado: (2010)

Glucocorticoid receptor mutations and clinical sensitivity to glucocorticoid in Chinese multiple sclerosis patients
por: Song, Tian, et al.
Publicado: (2020)

Glucocorticoid Receptor Activation in Lobular Breast Cancer Is Associated with Reduced Cell Proliferation and Promotion of Metastases
por: Porter, Baylee A., et al.
Publicado: (2023)

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor
por: Anacker, C, et al.
Publicado: (2011)

Peroxisome Proliferator-Activated Receptor-γ Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids
por: Heming, Michael, et al.
Publicado: (2018)

Induction of Metastatic Gastric Cancer by Peroxisome Proliferator-Activated Receptorδ Activation
por: Pollock, Claire B., et al.
Publicado: (2010)

Colon cancer cells produce immunoregulatory glucocorticoids
por: Sidler, Daniel, et al.
Publicado: (2012)

Exosomal miR-21 promotes proliferation, invasion and therapy resistance of colon adenocarcinoma cells through its target PDCD4
por: Sun, Li-Hua, et al.
Publicado: (2020)

Glucocorticoid receptor beta increases migration of human bladder cancer cells
por: McBeth, Lucien, et al.
Publicado: (2016)

Terminal deoxynucleotidyl transferase activities and glucocorticoid receptors in leukaemia.
por: Sasaki, R., et al.
Publicado: (1981)

Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury
por: Zhou, Han, et al.
Publicado: (2017)

Glucocorticoid receptor signalling activates YAP in breast cancer
por: Sorrentino, Giovanni, et al.
Publicado: (2017)

How does stress affect human being—a molecular dynamic simulation study on cortisol and its glucocorticoid receptor
por: Zhang, Dan, et al.
Publicado: (2017)

RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination
por: Ren, Ying, et al.
Publicado: (2019)

Selective glucocorticoid receptor-activating adjuvant therapy in cancer treatments
por: Sundahl, Nora, et al.
Publicado: (2016)

miR-141 promotes colon cancer cell proliferation by inhibiting MAP2K4
por: Ding, Lei, et al.
Publicado: (2017)

Role of Glucocorticoids and Glucocorticoid Receptors in Glaucoma Pathogenesis
por: Patel, Pinkal D., et al.
Publicado: (2023)

Tetramethylpyrazine inhibits proliferation of colon cancer cells in vitro
por: Li, Hua, et al.
Publicado: (2021)

The glucocorticoid receptor signalling in breast cancer
por: Moutsatsou, Paraskevi, et al.
Publicado: (2008)

Glucocorticoid Mediated Transcriptional Activity in Human Corneal Epithelial Cells Lacking the Glucocorticoid Receptor
por: Jonsson, Andrea Joyce, et al.
Publicado: (2021)

The role of glucocorticoids in increasing cardiovascular risk
por: Deng, Hai-Wei, et al.
Publicado: (2023)

Dexamethasone affects cell growth/apoptosis/chemosensitivity of colon cancer via glucocorticoid receptor α/NF-κB
por: He, Jianming, et al.
Publicado: (2017)

Selective Activator of the Glucocorticoid Receptor Compound A Dissociates Therapeutic and Atrophogenic Effects of Glucocorticoid Receptor Signaling in Skin
por: Klopot, Anna, et al.
Publicado: (2015)

Collagen Kinase Receptors as Potential Therapeutic Targets in Metastatic Colon Cancer
por: Lafitte, Marie, et al.
Publicado: (2020)

Insight into glucocorticoid receptor signalling through interactome model analysis
por: Bakker, Emyr, et al.
Publicado: (2017)

Role of mitochondrial glucocorticoid receptor in glucocorticoid-induced apoptosis
por: Sionov, Ronit Vogt, et al.
Publicado: (2006)

Heme Oxygenase 1 Impairs Glucocorticoid Receptor Activity in Prostate Cancer
por: Leonardi, Daiana B., et al.
Publicado: (2019)

Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2
por: Darmoul, D, et al.
Publicado: (2001)

Selective Activation of M(1) Muscarinic Receptors Attenuates Human Colon Cancer Cell Proliferation
por: Sundel, Margaret H., et al.
Publicado: (2023)

Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor
por: Drebert, Zuzanna, et al.
Publicado: (2017)

Up-regulation of CNDP2 facilitates the proliferation of colon cancer
por: Xue, Conglong, et al.
Publicado: (2014)

Metastatic Gastric Cancer to the Colon
por: Then, Eric Omar, et al.
Publicado: (2021)

Pseudopterosin Inhibits Proliferation and 3D Invasion in Triple-Negative Breast Cancer by Agonizing Glucocorticoid Receptor Alpha
por: Sperlich, Julia, et al.
Publicado: (2018)

Environmental signals perceived by the brain abate pro-metastatic monocytes by dampening glucocorticoids receptor signaling
por: Canali, María Magdalena, et al.
Publicado: (2023)

Downregulation of Activin A Receptor Type 2A Is Associated with Metastatic Potential and Poor Prognosis of Colon Cancer
por: Zhuo, Changhua, et al.
Publicado: (2018)

Involvement of the Androgen and Glucocorticoid Receptors in Bladder Cancer
por: McBeth, Lucien, et al.
Publicado: (2015)

miR-194 Inhibits the Proliferation of SW620 Colon Cancer Stem Cells Through Downregulation of SSH2 Expression
por: Sun, Bo, et al.
Publicado: (2019)

A mechanically-induced colon cancer cell population shows increased metastatic potential
por: Tang, Xin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3ekv630uhalkpqtvu2g5ss2eu8