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Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer’s Disease Neurons by Imposed External Cys/CySS Redox Shifts
Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD(+)) are critical for maintaining redox homeostasis. Aging as a major risk factor for Alzheimer’s disease...
Autores principales: | Dong, Yue, Sameni, Sara, Digman, Michelle A., Brewer, Gregory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677822/ https://www.ncbi.nlm.nih.gov/pubmed/31375701 http://dx.doi.org/10.1038/s41598-019-47582-x |
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