Cargando…

Gardnerella vaginalis causing pulmonary infection in a young adult: A novel case

Gardnerella vaginalis is an anaerobic, gram-variable bacterium primarily found in vaginal microflora of women. Previous reports of G. vaginalis cultured in men are few and have primarily been limited to the gastrointestinal and genitourinary tract.(2−4) Few reports of G. vaginalis causing severe inf...

Descripción completa

Detalles Bibliográficos
Autores principales: Bittar, Julie M, Gazzetta, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677925/
https://www.ncbi.nlm.nih.gov/pubmed/31388484
http://dx.doi.org/10.1016/j.rmcr.2019.100916
_version_ 1783440982779363328
author Bittar, Julie M
Gazzetta, Joshua
author_facet Bittar, Julie M
Gazzetta, Joshua
author_sort Bittar, Julie M
collection PubMed
description Gardnerella vaginalis is an anaerobic, gram-variable bacterium primarily found in vaginal microflora of women. Previous reports of G. vaginalis cultured in men are few and have primarily been limited to the gastrointestinal and genitourinary tract.(2−4) Few reports of G. vaginalis causing severe infections have been reported in the literature, including septicemia(7) and two cases of perinephric abscess.(8,9) There has been one previously reported case of G. vaginalis causing pulmonary complications that occurred in a male alcohol abuser. In our case review, we aim to demonstrate an unusual source of a pulmonary infection and highlight the importance of proper microbial isolation to guide treatment. Our patient is a young male who presented following multiple gunshot wounds including one to his head causing an intracranial hemorrhage, hydrocephalus, and a dural sinus thrombosis. His hospital course was complicated by a decline in neurological status treated with a craniotomy and external drain placement and multiple pulmonary infections. During his fever work-ups, he found to have G. vaginalis on mini-bronchoalveolar lavage and was subsequently treated with metronidazole. After treating his G. vaginalis pneumonia and other infectious sources, namely Haemaphilus influenzae and coagulase-negative staphylococcus pneumonias, his fevers and leukocytosis resolved and he was successfully discharged to a rehabilitation facility for neurologic recovery. To our knowledge, this is the second reported case of G. vaginalis isolated from a pulmonary culture and the first in a previously healthy, immunocompetent young male outside of the urinary tract.
format Online
Article
Text
id pubmed-6677925
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-66779252019-08-06 Gardnerella vaginalis causing pulmonary infection in a young adult: A novel case Bittar, Julie M Gazzetta, Joshua Respir Med Case Rep Case Report Gardnerella vaginalis is an anaerobic, gram-variable bacterium primarily found in vaginal microflora of women. Previous reports of G. vaginalis cultured in men are few and have primarily been limited to the gastrointestinal and genitourinary tract.(2−4) Few reports of G. vaginalis causing severe infections have been reported in the literature, including septicemia(7) and two cases of perinephric abscess.(8,9) There has been one previously reported case of G. vaginalis causing pulmonary complications that occurred in a male alcohol abuser. In our case review, we aim to demonstrate an unusual source of a pulmonary infection and highlight the importance of proper microbial isolation to guide treatment. Our patient is a young male who presented following multiple gunshot wounds including one to his head causing an intracranial hemorrhage, hydrocephalus, and a dural sinus thrombosis. His hospital course was complicated by a decline in neurological status treated with a craniotomy and external drain placement and multiple pulmonary infections. During his fever work-ups, he found to have G. vaginalis on mini-bronchoalveolar lavage and was subsequently treated with metronidazole. After treating his G. vaginalis pneumonia and other infectious sources, namely Haemaphilus influenzae and coagulase-negative staphylococcus pneumonias, his fevers and leukocytosis resolved and he was successfully discharged to a rehabilitation facility for neurologic recovery. To our knowledge, this is the second reported case of G. vaginalis isolated from a pulmonary culture and the first in a previously healthy, immunocompetent young male outside of the urinary tract. Elsevier 2019-07-25 /pmc/articles/PMC6677925/ /pubmed/31388484 http://dx.doi.org/10.1016/j.rmcr.2019.100916 Text en © 2019 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bittar, Julie M
Gazzetta, Joshua
Gardnerella vaginalis causing pulmonary infection in a young adult: A novel case
title Gardnerella vaginalis causing pulmonary infection in a young adult: A novel case
title_full Gardnerella vaginalis causing pulmonary infection in a young adult: A novel case
title_fullStr Gardnerella vaginalis causing pulmonary infection in a young adult: A novel case
title_full_unstemmed Gardnerella vaginalis causing pulmonary infection in a young adult: A novel case
title_short Gardnerella vaginalis causing pulmonary infection in a young adult: A novel case
title_sort gardnerella vaginalis causing pulmonary infection in a young adult: a novel case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677925/
https://www.ncbi.nlm.nih.gov/pubmed/31388484
http://dx.doi.org/10.1016/j.rmcr.2019.100916
work_keys_str_mv AT bittarjuliem gardnerellavaginaliscausingpulmonaryinfectioninayoungadultanovelcase
AT gazzettajoshua gardnerellavaginaliscausingpulmonaryinfectioninayoungadultanovelcase