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Predicting the Functional Outcome of Adult Patients with Status Epilepticus

Patients that survive status epilepticus (SE) may suffer from neurological and cognitive deficits that cause severe disabilities. An effective scoring system for functional outcome prediction may help the clinician in making treatment decisions for SE patients. Three scoring systems, namely the Stat...

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Autores principales: Lin, Chih-Hsiang, Ho, Chen-Jui, Lu, Yan-Ting, Shih, Fu-Yuan, Chuang, Yao-Chung, Tsai, Meng-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678186/
https://www.ncbi.nlm.nih.gov/pubmed/31288449
http://dx.doi.org/10.3390/jcm8070992
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author Lin, Chih-Hsiang
Ho, Chen-Jui
Lu, Yan-Ting
Shih, Fu-Yuan
Chuang, Yao-Chung
Tsai, Meng-Han
author_facet Lin, Chih-Hsiang
Ho, Chen-Jui
Lu, Yan-Ting
Shih, Fu-Yuan
Chuang, Yao-Chung
Tsai, Meng-Han
author_sort Lin, Chih-Hsiang
collection PubMed
description Patients that survive status epilepticus (SE) may suffer from neurological and cognitive deficits that cause severe disabilities. An effective scoring system for functional outcome prediction may help the clinician in making treatment decisions for SE patients. Three scoring systems, namely the Status Epilepticus Severity Score (STESS), the Epidemiology-Based Mortality Score in Status Epilepticus (EMSE), and the Encephalitis-Nonconvulsive Status Epilepticus-Diazepam Resistance-Image Abnormalities-Tracheal Intubation (END-IT), have been developed in the past decade to predict the outcomes of patients with SE. Our study aimed at evaluating the effectiveness of these scores in predicting the function outcomes both at and after discharge in SE patients. We retrospectively reviewed the clinical data of 55 patients admitted to our neurological intensive care unit between January 2017 and December 2017. The clinical outcomes at discharge and at last follow-up were graded using the modified Rankin Scale. Our research indicated that STESS was the most sensitive and EMSE was the most specific predictive scoring method for SE outcome prediction. On the other hand, END-IT predicted functional outcomes in SE patients poorly. We concluded that STESS and EMSE can accurately predict the functional outcomes in SE patients both at discharge and the follow-up period.
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spelling pubmed-66781862019-08-19 Predicting the Functional Outcome of Adult Patients with Status Epilepticus Lin, Chih-Hsiang Ho, Chen-Jui Lu, Yan-Ting Shih, Fu-Yuan Chuang, Yao-Chung Tsai, Meng-Han J Clin Med Article Patients that survive status epilepticus (SE) may suffer from neurological and cognitive deficits that cause severe disabilities. An effective scoring system for functional outcome prediction may help the clinician in making treatment decisions for SE patients. Three scoring systems, namely the Status Epilepticus Severity Score (STESS), the Epidemiology-Based Mortality Score in Status Epilepticus (EMSE), and the Encephalitis-Nonconvulsive Status Epilepticus-Diazepam Resistance-Image Abnormalities-Tracheal Intubation (END-IT), have been developed in the past decade to predict the outcomes of patients with SE. Our study aimed at evaluating the effectiveness of these scores in predicting the function outcomes both at and after discharge in SE patients. We retrospectively reviewed the clinical data of 55 patients admitted to our neurological intensive care unit between January 2017 and December 2017. The clinical outcomes at discharge and at last follow-up were graded using the modified Rankin Scale. Our research indicated that STESS was the most sensitive and EMSE was the most specific predictive scoring method for SE outcome prediction. On the other hand, END-IT predicted functional outcomes in SE patients poorly. We concluded that STESS and EMSE can accurately predict the functional outcomes in SE patients both at discharge and the follow-up period. MDPI 2019-07-08 /pmc/articles/PMC6678186/ /pubmed/31288449 http://dx.doi.org/10.3390/jcm8070992 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Chih-Hsiang
Ho, Chen-Jui
Lu, Yan-Ting
Shih, Fu-Yuan
Chuang, Yao-Chung
Tsai, Meng-Han
Predicting the Functional Outcome of Adult Patients with Status Epilepticus
title Predicting the Functional Outcome of Adult Patients with Status Epilepticus
title_full Predicting the Functional Outcome of Adult Patients with Status Epilepticus
title_fullStr Predicting the Functional Outcome of Adult Patients with Status Epilepticus
title_full_unstemmed Predicting the Functional Outcome of Adult Patients with Status Epilepticus
title_short Predicting the Functional Outcome of Adult Patients with Status Epilepticus
title_sort predicting the functional outcome of adult patients with status epilepticus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678186/
https://www.ncbi.nlm.nih.gov/pubmed/31288449
http://dx.doi.org/10.3390/jcm8070992
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