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The Aberrant Expression of the Mesenchymal Variant of FGFR2 in the Epithelial Context Inhibits Autophagy

Signaling of the epithelial splice variant of fibroblast growth factor receptor 2 (FGFR2b) triggers both differentiation and autophagy, while the aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells induces impaired differentiation, epithelial mesenchymal transition (EMT) and tu...

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Detalles Bibliográficos
Autores principales: Nanni, Monica, Ranieri, Danilo, Persechino, Flavia, Torrisi, Maria Rosaria, Belleudi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678203/
https://www.ncbi.nlm.nih.gov/pubmed/31261937
http://dx.doi.org/10.3390/cells8070653