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Possible Involvement of Intracellular Calcium-Independent Phospholipase A(2) in the Release of Secretory Phospholipases from Mast Cells—Increased Expression in Ileal Mast Cells of Crohn’s Disease

Increased activity of secretory phospholipases A(2) (sPLA(2)) type-II was previously observed in ileum of Crohn’s disease (CD). Our aims were to explore the involvement of calcium-independent (i)PLA(2)β in the release of sPLA(2)s from the human mast cell (MC) line (HMC-1) and investigate expressions...

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Detalles Bibliográficos
Autores principales: Christerson, Ulrika, Keita, Åsa V., Winberg, Martin E., Söderholm, Johan D., Gustafson-Svärd, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678282/
https://www.ncbi.nlm.nih.gov/pubmed/31277247
http://dx.doi.org/10.3390/cells8070672