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Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates
Medulloblastoma is a common pediatric brain tumor and one of the main types of solid cancers in children below the age of 10. Recently, cholesterol-lowering “statin” drugs have been highlighted for their possible anti-cancer effects. Clinically, statins are reported to have promising potential for c...
Autores principales: | Sheikholeslami, Kimia, Ali Sher, Annan, Lockman, Sandhini, Kroft, Daniel, Ganjibakhsh, Meysam, Nejati-Koshki, Kazem, Shojaei, Shahla, Ghavami, Saeid, Rastegar, Mojgan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678292/ https://www.ncbi.nlm.nih.gov/pubmed/31319483 http://dx.doi.org/10.3390/cancers11070994 |
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