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Super-Resolution Microscopy of Chromatin
Since the advent of super-resolution microscopy, countless approaches and studies have been published contributing significantly to our understanding of cellular processes. With the aid of chromatin-specific fluorescence labeling techniques, we are gaining increasing insight into gene regulation and...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678334/ https://www.ncbi.nlm.nih.gov/pubmed/31261775 http://dx.doi.org/10.3390/genes10070493 |
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author | Birk, Udo J. |
author_facet | Birk, Udo J. |
author_sort | Birk, Udo J. |
collection | PubMed |
description | Since the advent of super-resolution microscopy, countless approaches and studies have been published contributing significantly to our understanding of cellular processes. With the aid of chromatin-specific fluorescence labeling techniques, we are gaining increasing insight into gene regulation and chromatin organization. Combined with super-resolution imaging and data analysis, these labeling techniques enable direct assessment not only of chromatin interactions but also of the function of specific chromatin conformational states. |
format | Online Article Text |
id | pubmed-6678334 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66783342019-08-19 Super-Resolution Microscopy of Chromatin Birk, Udo J. Genes (Basel) Review Since the advent of super-resolution microscopy, countless approaches and studies have been published contributing significantly to our understanding of cellular processes. With the aid of chromatin-specific fluorescence labeling techniques, we are gaining increasing insight into gene regulation and chromatin organization. Combined with super-resolution imaging and data analysis, these labeling techniques enable direct assessment not only of chromatin interactions but also of the function of specific chromatin conformational states. MDPI 2019-06-28 /pmc/articles/PMC6678334/ /pubmed/31261775 http://dx.doi.org/10.3390/genes10070493 Text en © 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Birk, Udo J. Super-Resolution Microscopy of Chromatin |
title | Super-Resolution Microscopy of Chromatin |
title_full | Super-Resolution Microscopy of Chromatin |
title_fullStr | Super-Resolution Microscopy of Chromatin |
title_full_unstemmed | Super-Resolution Microscopy of Chromatin |
title_short | Super-Resolution Microscopy of Chromatin |
title_sort | super-resolution microscopy of chromatin |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678334/ https://www.ncbi.nlm.nih.gov/pubmed/31261775 http://dx.doi.org/10.3390/genes10070493 |
work_keys_str_mv | AT birkudoj superresolutionmicroscopyofchromatin |