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Cancer Testis Antigens and Immunotherapy: Where Do We Stand in the Targeting of PRAME?

PRAME or PReferentially expressed Antigen in Melanoma is a testis-selective cancer testis antigen (CTA) with restricted expression in somatic tissues and re-expression in various cancers. It is one of the most widely studied CTAs and has been associated with the outcome and risk of metastasis. Altho...

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Detalles Bibliográficos
Autores principales: Al-Khadairi, Ghaneya, Decock, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678383/
https://www.ncbi.nlm.nih.gov/pubmed/31311081
http://dx.doi.org/10.3390/cancers11070984