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Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback

Much of animal-associated microbiome research has been conducted in species for which little is known of their natural ecology and evolution. Microbiome studies that combine population genetic, environment, and geographic data for wild organisms can be very informative, especially in situations wher...

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Autores principales: Steury, Robert A., Currey, Mark C., Cresko, William A., Bohannan, Brendan J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678413/
https://www.ncbi.nlm.nih.gov/pubmed/31248008
http://dx.doi.org/10.3390/genes10070484
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author Steury, Robert A.
Currey, Mark C.
Cresko, William A.
Bohannan, Brendan J. M.
author_facet Steury, Robert A.
Currey, Mark C.
Cresko, William A.
Bohannan, Brendan J. M.
author_sort Steury, Robert A.
collection PubMed
description Much of animal-associated microbiome research has been conducted in species for which little is known of their natural ecology and evolution. Microbiome studies that combine population genetic, environment, and geographic data for wild organisms can be very informative, especially in situations where host genetic variation and the environment both influence microbiome variation. The few studies that have related population genetic and microbiome variation in wild populations have been constrained by observation-based kinship data or incomplete genomic information. Here we integrate population genomic and microbiome analyses in wild threespine stickleback fish distributed throughout western Oregon, USA. We found that gut microbiome diversity and composition partitioned more among than within wild host populations and was better explained by host population genetic divergence than by environment and geography. We also identified gut microbial taxa that were most differentially abundant across environments and across genetically divergent populations. Our findings highlight the benefits of studies that investigate host-associated microbiomes in wild organisms.
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spelling pubmed-66784132019-08-19 Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback Steury, Robert A. Currey, Mark C. Cresko, William A. Bohannan, Brendan J. M. Genes (Basel) Article Much of animal-associated microbiome research has been conducted in species for which little is known of their natural ecology and evolution. Microbiome studies that combine population genetic, environment, and geographic data for wild organisms can be very informative, especially in situations where host genetic variation and the environment both influence microbiome variation. The few studies that have related population genetic and microbiome variation in wild populations have been constrained by observation-based kinship data or incomplete genomic information. Here we integrate population genomic and microbiome analyses in wild threespine stickleback fish distributed throughout western Oregon, USA. We found that gut microbiome diversity and composition partitioned more among than within wild host populations and was better explained by host population genetic divergence than by environment and geography. We also identified gut microbial taxa that were most differentially abundant across environments and across genetically divergent populations. Our findings highlight the benefits of studies that investigate host-associated microbiomes in wild organisms. MDPI 2019-06-26 /pmc/articles/PMC6678413/ /pubmed/31248008 http://dx.doi.org/10.3390/genes10070484 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Steury, Robert A.
Currey, Mark C.
Cresko, William A.
Bohannan, Brendan J. M.
Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback
title Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback
title_full Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback
title_fullStr Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback
title_full_unstemmed Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback
title_short Population Genetic Divergence and Environment Influence the Gut Microbiome in Oregon Threespine Stickleback
title_sort population genetic divergence and environment influence the gut microbiome in oregon threespine stickleback
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678413/
https://www.ncbi.nlm.nih.gov/pubmed/31248008
http://dx.doi.org/10.3390/genes10070484
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