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Spatiotemporal pH Heterogeneity as a Promoter of Cancer Progression and Therapeutic Resistance
Dysregulation of pH in solid tumors is a hallmark of cancer. In recent years, the role of altered pH heterogeneity in space, between benign and aggressive tissues, between individual cancer cells, and between subcellular compartments, has been steadily elucidated. Changes in temporal pH-related proc...
Autores principales: | Korenchan, David E., Flavell, Robert R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678451/ https://www.ncbi.nlm.nih.gov/pubmed/31330859 http://dx.doi.org/10.3390/cancers11071026 |
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