An NF-kappaB- and IKK-Independent Function of NEMO Prevents Hepatocarcinogenesis by Suppressing Compensatory Liver Regeneration

The I-κB-Kinase (IKK) complex represents a central signaling nexus in the TNF-dependent activation of the pro-inflammatory NF-κB pathway. However, recent studies suggested that the distinct IKK subunits (IKKα, IKKβ, and NEMO) might withhold additional NF-κB-independent functions in inflammation and...

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Detalles Bibliográficos
Autores principales: Koppe, Christiane, Reisinger, Florian, Wehr, Karina, Vucur, Mihael, Trautwein, Christian, Tacke, Frank, Heikenwalder, Mathias, Luedde, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678501/
https://www.ncbi.nlm.nih.gov/pubmed/31319593
http://dx.doi.org/10.3390/cancers11070999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678501/
https://www.ncbi.nlm.nih.gov/pubmed/31319593
http://dx.doi.org/10.3390/cancers11070999

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