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Phosphorene Is the New Graphene in Biomedical Applications

Nowadays, the research of smart materials is focusing on the allotropics, which have specific characteristics that are useful in several areas, including biomedical applications. In recent years, graphene has revealed interesting antibacterial and physical peculiarities, but it has also shown limita...

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Autores principales: Tatullo, Marco, Genovese, Fabio, Aiello, Elisabetta, Amantea, Massimiliano, Makeeva, Irina, Zavan, Barbara, Rengo, Sandro, Fortunato, Leonzio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678593/
https://www.ncbi.nlm.nih.gov/pubmed/31323844
http://dx.doi.org/10.3390/ma12142301
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author Tatullo, Marco
Genovese, Fabio
Aiello, Elisabetta
Amantea, Massimiliano
Makeeva, Irina
Zavan, Barbara
Rengo, Sandro
Fortunato, Leonzio
author_facet Tatullo, Marco
Genovese, Fabio
Aiello, Elisabetta
Amantea, Massimiliano
Makeeva, Irina
Zavan, Barbara
Rengo, Sandro
Fortunato, Leonzio
author_sort Tatullo, Marco
collection PubMed
description Nowadays, the research of smart materials is focusing on the allotropics, which have specific characteristics that are useful in several areas, including biomedical applications. In recent years, graphene has revealed interesting antibacterial and physical peculiarities, but it has also shown limitations. Black phosphorus has structural and biochemical properties that make it ideal for biomedical applications: 2D sheets of black phosphorus are called Black Phosphorene (BP), and it could replace graphene in the coming years. BP, similar to other 2D materials, can be used for colorimetric and fluorescent detectors, as well as for biosensing devices. BP also shows high in vivo biodegradability, producing non-toxic agents in the body. This characteristic is promising for pharmacological applications, as well as for scaffold and prosthetic coatings. BP shows low cytotoxicity, thus avoiding the induction of local inflammation or toxicity. As such, BP is a good candidate for different applications in the biomedical sector. Properties such as biocompatibility, biodegradability, and biosafety are essential for use in medicine. In this review, we have exploited all such aspects, also comparing BP with other similar materials, such as the well-known graphene.
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spelling pubmed-66785932019-08-19 Phosphorene Is the New Graphene in Biomedical Applications Tatullo, Marco Genovese, Fabio Aiello, Elisabetta Amantea, Massimiliano Makeeva, Irina Zavan, Barbara Rengo, Sandro Fortunato, Leonzio Materials (Basel) Review Nowadays, the research of smart materials is focusing on the allotropics, which have specific characteristics that are useful in several areas, including biomedical applications. In recent years, graphene has revealed interesting antibacterial and physical peculiarities, but it has also shown limitations. Black phosphorus has structural and biochemical properties that make it ideal for biomedical applications: 2D sheets of black phosphorus are called Black Phosphorene (BP), and it could replace graphene in the coming years. BP, similar to other 2D materials, can be used for colorimetric and fluorescent detectors, as well as for biosensing devices. BP also shows high in vivo biodegradability, producing non-toxic agents in the body. This characteristic is promising for pharmacological applications, as well as for scaffold and prosthetic coatings. BP shows low cytotoxicity, thus avoiding the induction of local inflammation or toxicity. As such, BP is a good candidate for different applications in the biomedical sector. Properties such as biocompatibility, biodegradability, and biosafety are essential for use in medicine. In this review, we have exploited all such aspects, also comparing BP with other similar materials, such as the well-known graphene. MDPI 2019-07-18 /pmc/articles/PMC6678593/ /pubmed/31323844 http://dx.doi.org/10.3390/ma12142301 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tatullo, Marco
Genovese, Fabio
Aiello, Elisabetta
Amantea, Massimiliano
Makeeva, Irina
Zavan, Barbara
Rengo, Sandro
Fortunato, Leonzio
Phosphorene Is the New Graphene in Biomedical Applications
title Phosphorene Is the New Graphene in Biomedical Applications
title_full Phosphorene Is the New Graphene in Biomedical Applications
title_fullStr Phosphorene Is the New Graphene in Biomedical Applications
title_full_unstemmed Phosphorene Is the New Graphene in Biomedical Applications
title_short Phosphorene Is the New Graphene in Biomedical Applications
title_sort phosphorene is the new graphene in biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678593/
https://www.ncbi.nlm.nih.gov/pubmed/31323844
http://dx.doi.org/10.3390/ma12142301
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