Cargando…
Reactions in the Radiosensitizer Misonidazole Induced by Low-Energy (0–10 eV) Electrons
Misonidazole (MISO) was considered as radiosensitizer for the treatment of hypoxic tumors. A prerequisite for entering a hypoxic cell is reduction of the drug, which may occur in the early physical-chemical stage of radiation damage. Here we study electron attachment to MISO and find that it very ef...
Autores principales: | Meißner, Rebecca, Feketeová, Linda, Illenberger, Eugen, Denifl, Stephan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678818/ https://www.ncbi.nlm.nih.gov/pubmed/31315268 http://dx.doi.org/10.3390/ijms20143496 |
Ejemplares similares
-
Reactions in Nitroimidazole Triggered by Low-Energy (0–2 eV) Electrons: Methylation at N1-H Completely Blocks Reactivity**
por: Tanzer, Katrin, et al.
Publicado: (2014) -
Low-energy electrons transform the nimorazole molecule into a radiosensitiser
por: Meißner, Rebecca, et al.
Publicado: (2019) -
Ring Formation and Hydration Effects in Electron Attachment to Misonidazole
por: Ončák, Milan, et al.
Publicado: (2019) -
Positive and negative ions of the amino acid histidine formed in low‐energy electron collisions
por: Meißner, Rebecca, et al.
Publicado: (2019) -
Electron Ionization of Imidazole and Its Derivative 2-Nitroimidazole
por: Meißner, Rebecca, et al.
Publicado: (2019)