X-rays Activate Telomeric Homologous Recombination Mediated Repair in Primary Cells

Cancer cells need to acquire telomere maintenance mechanisms in order to counteract progressive telomere shortening due to multiple rounds of replication. Most human tumors maintain their telomeres expressing telomerase whereas the remaining 15%–20% utilize the alternative lengthening of telomeres (...

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Detalles Bibliográficos
Autores principales: De Vitis, Marco, Berardinelli, Francesco, Coluzzi, Elisa, Marinaccio, Jessica, O’Sullivan, Roderick J., Sgura, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678842/
https://www.ncbi.nlm.nih.gov/pubmed/31336873
http://dx.doi.org/10.3390/cells8070708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678842/
https://www.ncbi.nlm.nih.gov/pubmed/31336873
http://dx.doi.org/10.3390/cells8070708

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