Targeting Tyrosine Phosphatases by 3-Bromopyruvate Overcomes Hyperactivation of Platelets from Gastrointestinal Cancer Patients

Venous thromboembolism (VTE) is one of the most common causes of cancer related mortality. It has been speculated that hypercoagulation in cancer patients is triggered by direct or indirect contact of platelets with tumor cells, however the underlying molecular mechanisms involved are currently unkn...

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Detalles Bibliográficos
Autores principales: Faria, Alessandra V. S., Andrade, Sheila S., Reijm, Agnes N., Spaander, Manon C. W., de Maat, Moniek P. M., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V., Fuhler, Gwenny M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678874/
https://www.ncbi.nlm.nih.gov/pubmed/31261776
http://dx.doi.org/10.3390/jcm8070936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678874/
https://www.ncbi.nlm.nih.gov/pubmed/31261776
http://dx.doi.org/10.3390/jcm8070936

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