Cargando…
A Novel Assay for Profiling GBM Cancer Model Heterogeneity and Drug Screening
Accurate patient-derived models of cancer are needed for profiling the disease and for testing therapeutics. These models must not only be accurate, but also suitable for high-throughput screening and analysis. Here we compare two derivative cancer models, microtumors and spheroids, to the gold stan...
Autores principales: | Stackhouse, Christian T., Rowland, James R., Shevin, Rachael S., Singh, Raj, Gillespie, G. Yancey, Willey, Christopher D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678976/ https://www.ncbi.nlm.nih.gov/pubmed/31336733 http://dx.doi.org/10.3390/cells8070702 |
Ejemplares similares
-
Exploring the Roles of lncRNAs in GBM Pathophysiology and Their Therapeutic Potential
por: Stackhouse, Christian T., et al.
Publicado: (2020) -
Combinatorial Drug Testing in 3D Microtumors Derived from GBM Patient-Derived Xenografts Reveals Cytotoxic Synergy in Pharmacokinomics-informed Pathway Interactions
por: Gilbert, Ashley N., et al.
Publicado: (2018) -
CBMS-7 IGF1/N-cadherin/Clusterin signaling axis mediates adaptive radioresistance of glioma stem cells
por: Osuka, Satoru, et al.
Publicado: (2021) -
Drug Screening of Human GBM Spheroids in Brain Cancer Chip
por: Akay, Metin, et al.
Publicado: (2018) -
Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM
por: Liu, Bao, et al.
Publicado: (2022)