Ciliopathy-Associated Protein Kinase ICK Requires Its Non-Catalytic Carboxyl-Terminal Domain for Regulation of Ciliogenesis

Loss-of-function mutations in the human ICK (intestinal cell kinase) gene cause dysfunctional primary cilia and perinatal lethality which are associated with human ciliopathies. The enzyme that we herein call CAPK (ciliopathy-associated protein kinase) is a serine/threonine protein kinase that has a...

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Detalles Bibliográficos
Autores principales: Oh, Yoon Seon, Wang, Eric J., Gailey, Casey D., Brautigan, David L., Allen, Benjamin L., Fu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678984/
https://www.ncbi.nlm.nih.gov/pubmed/31277411
http://dx.doi.org/10.3390/cells8070677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678984/
https://www.ncbi.nlm.nih.gov/pubmed/31277411
http://dx.doi.org/10.3390/cells8070677

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