Combined Treatment with MEK and mTOR Inhibitors is Effective in In Vitro and In Vivo Models of Hepatocellular Carcinoma

Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer histotype, characterized by high biological aggressiveness and scarce treatment options. Recently, we have established a clinically relevant murine HCC model by co-expressing activated forms of v-akt murine thymoma vi...

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Detalles Bibliográficos
Autores principales: Liu, Xianqiong, Hu, Junjie, Song, Xinhua, Utpatel, Kirsten, Zhang, Yi, Wang, Pan, Lu, Xinjun, Zhang, Jie, Xu, Meng, Su, Tao, Che, Li, Wang, Jingxiao, Evert, Matthias, Calvisi, Diego F., Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679026/
https://www.ncbi.nlm.nih.gov/pubmed/31277283
http://dx.doi.org/10.3390/cancers11070930

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