Cargando…

Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders

Extracellular vesicles (EVs) have received increasing attention over the last two decades. Initially, they were considered as just a garbage disposal tool; however, it has progressively become clear that their protein, nucleic acid (namely miRNA and mRNA), and lipid contents have signaling functions...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tancini, Brunella, Buratta, Sandra, Sagini, Krizia, Costanzi, Eva, Delo, Federica, Urbanelli, Lorena, Emiliani, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679199/ https://www.ncbi.nlm.nih.gov/pubmed/31284546 http://dx.doi.org/10.3390/genes10070510

Ejemplares similares

Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular
por: Buratta, Sandra, et al.
Publicado: (2020)

The Role of Extracellular Vesicles in Viral Infection and Transmission
por: Urbanelli, Lorena, et al.
Publicado: (2019)

Lysosomal Exocytosis: The Extracellular Role of an Intracellular Organelle
por: Tancini, Brunella, et al.
Publicado: (2020)

Extracellular Vesicles as New Players in Cellular Senescence
por: Urbanelli, Lorena, et al.
Publicado: (2016)

Drug-Induced Lysosomal Impairment Is Associated with the Release of Extracellular Vesicles Carrying Autophagy Markers
por: Sagini, Krizia, et al.
Publicado: (2021)

Extracellular Vesicles as Conveyors of Membrane-Derived Bioactive Lipids in Immune System
por: Sagini, Krizia, et al.
Publicado: (2018)

Oncogenic H-Ras Expression Induces Fatty Acid Profile Changes in Human Fibroblasts and Extracellular Vesicles
por: Sagini, Krizia, et al.
Publicado: (2018)

Extracellular Vesicles under Oxidative Stress Conditions: Biological Properties and Physiological Roles
por: Chiaradia, Elisabetta, et al.
Publicado: (2021)

Signaling Pathways in Exosomes Biogenesis, Secretion and Fate
por: Urbanelli, Lorena, et al.
Publicado: (2013)

Extracellular vesicles released by fibroblasts undergoing H-Ras induced senescence show changes in lipid profile
por: Buratta, Sandra, et al.
Publicado: (2017)

Lipid Biomarkers in Liquid Biopsies: Novel Opportunities for Cancer Diagnosis
por: Sagini, Krizia, et al.
Publicado: (2023)

The n-10 Fatty Acids Family in the Lipidome of Human Prostatic Adenocarcinoma Cell Membranes and Extracellular Vesicles
por: Ferreri, Carla, et al.
Publicado: (2020)

Oncogenic H-Ras Up-Regulates Acid β-Hexosaminidase by a Mechanism Dependent on the Autophagy Regulator TFEB
por: Urbanelli, Lorena, et al.
Publicado: (2014)

Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
por: Buratta, Sandra, et al.
Publicado: (2021)

Lipidomic analysis of cancer cells cultivated at acidic pH reveals phospholipid fatty acids remodelling associated with transcriptional reprogramming
por: Urbanelli, Lorena, et al.
Publicado: (2020)

Protein and Lipid Content of Milk Extracellular Vesicles: A Comparative Overview
por: Buratta, Sandra, et al.
Publicado: (2023)

Effect of Curcumin on Protein Damage Induced by Rotenone in Dopaminergic PC12 Cells
por: Buratta, Sandra, et al.
Publicado: (2020)

Extracellular Vesicles in Aging: An Emerging Hallmark?
por: Manni, Giorgia, et al.
Publicado: (2023)

Non-contact mechanical and chemical analysis of single living cells by microspectroscopic techniques
por: Mattana, Sara, et al.
Publicado: (2018)

Correlative Brillouin and Raman spectroscopy data acquired on single cells
por: Caponi, Silvia, et al.
Publicado: (2020)

hLGDB: a database of human lysosomal genes and their regulation
por: Brozzi, Alessandro, et al.
Publicado: (2013)

Curcumin Analogue C1 Promotes Hex and Gal Recruitment to the Plasma Membrane via mTORC1-Independent TFEB Activation
por: Magini, Alessandro, et al.
Publicado: (2019)

Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
por: Parfejevs, Vadims, et al.
Publicado: (2020)

Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders
por: Seras‐Franzoso, Joaquin, et al.
Publicado: (2021)

Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies
por: Calzoni, Eleonora, et al.
Publicado: (2019)

mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model
por: Polchi, Alice, et al.
Publicado: (2018)

Lysosomal storage disorders
por: Cabrera-Salazar, Mario A, et al.
Publicado: (2007)

Lysosomes and Lysosomal Storage Diseases
por: Noebels, Jeffrey L.
Publicado: (1981)

Lysosomal storage disorders: The cellular impact of lysosomal dysfunction
por: Platt, Frances M., et al.
Publicado: (2012)

Circulating extracellular particles from severe COVID-19 patients show altered profiling and innate lymphoid cell-modulating ability
por: Forte, Dorian, et al.
Publicado: (2023)

Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired
por: Liang, Wenjing, et al.
Publicado: (2023)

Autophagy in lysosomal storage disorders
por: Lieberman, Andrew P., et al.
Publicado: (2012)

Lysosomal Storage Disorders and Malignancy
por: Pastores, Gregory M., et al.
Publicado: (2017)

Lipidic Profile Changes in Exosomes and Microvesicles Derived From Plasma of Monoclonal Antibody-Treated Psoriatic Patients
por: Paolino, Giovanni, et al.
Publicado: (2022)

Extracellular Vesicles Released by Genetically Modified Macrophages Activate Autophagy and Produce Potent Neuroprotection in Mouse Model of Lysosomal Storage Disorder, Batten Disease
por: El-Hage, Nazira, et al.
Publicado: (2023)

Rapamycin Loaded Solid Lipid Nanoparticles as a New Tool to Deliver mTOR Inhibitors: Formulation and in Vitro Characterization
por: Polchi, Alice, et al.
Publicado: (2016)

The Role of Extracellular Vesicles as Shuttles of RNA and Their Clinical Significance as Biomarkers in Hepatocellular Carcinoma
por: Costanzi, Eva, et al.
Publicado: (2021)

HexA-Enzyme Coated Polymer Nanoparticles for the Development of a Drug-Delivery System in the Treatment of Sandhoff Lysosomal Storage Disease
por: Calzoni, Eleonora, et al.
Publicado: (2022)

Role of Ceramides and Lysosomes in Extracellular Vesicle Biogenesis, Cargo Sorting and Release
por: Horbay, Rostyslav, et al.
Publicado: (2022)

Mitochondrial Dysfunction in Lysosomal Storage Disorders
por: de la Mata, Mario, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6k4s5rtaq5qco1ulh9ds3aq7bj