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Synthesis and Evaluation of Novel Pyrazole Ethandiamide Compounds as Inhibitors of Human THP-1 Monocytic Cell Neurotoxicity

Neuroinflammation and microglia-mediated neurotoxicity contribute to the pathogenesis of a broad range of neurodegenerative diseases; therefore, identifying novel compounds that can suppress adverse activation of glia is an important goal. We have previously identified a class of trisubstituted pyra...

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Detalles Bibliográficos
Autores principales:	McKenzie, Jordan A., Barghash, Reham F., Alsaggaf, Azhaar T., Kulkarni, Omkar, Boudreau, Kalun, Menard, Frederic, Neeland, Edward G., Klegeris, Andis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679371/ https://www.ncbi.nlm.nih.gov/pubmed/31261948 http://dx.doi.org/10.3390/cells8070655

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