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Free-Energy Calculations for Bioisosteric Modifications of A(3) Adenosine Receptor Antagonists
Adenosine receptors are a family of G protein-coupled receptors with increased attention as drug targets on different indications. We investigate the thermodynamics of ligand binding to the A(3) adenosine receptor subtype, focusing on a recently reported series of diarylacetamidopyridine inhibitors...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679372/ https://www.ncbi.nlm.nih.gov/pubmed/31315296 http://dx.doi.org/10.3390/ijms20143499 |