Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish

The aberrant activation of developmental processes triggers diverse cancer types. Chordoma is a rare, aggressive tumor arising from transformed notochord remnants. Several potentially oncogenic factors have been found to be deregulated in chordoma, yet causation remains uncertain. In particular, sus...

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Detalles Bibliográficos
Autores principales: D'Agati, Gianluca, Cabello, Elena María, Frontzek, Karl, Rushing, Elisabeth J., Klemm, Robin, Robinson, Mark D., White, Richard M., Mosimann, Christian, Burger, Alexa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679381/
https://www.ncbi.nlm.nih.gov/pubmed/31221659
http://dx.doi.org/10.1242/dmm.039545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679381/
https://www.ncbi.nlm.nih.gov/pubmed/31221659
http://dx.doi.org/10.1242/dmm.039545

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