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Active receptor tyrosine kinases, but not Brachyury, are sufficient to trigger chordoma in zebrafish
The aberrant activation of developmental processes triggers diverse cancer types. Chordoma is a rare, aggressive tumor arising from transformed notochord remnants. Several potentially oncogenic factors have been found to be deregulated in chordoma, yet causation remains uncertain. In particular, sus...
Autores principales: | D'Agati, Gianluca, Cabello, Elena María, Frontzek, Karl, Rushing, Elisabeth J., Klemm, Robin, Robinson, Mark D., White, Richard M., Mosimann, Christian, Burger, Alexa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679381/ https://www.ncbi.nlm.nih.gov/pubmed/31221659 http://dx.doi.org/10.1242/dmm.039545 |
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