Cargando…
Modelling the MYC-driven normal-to-tumour switch in breast cancer
The potent MYC oncoprotein is deregulated in many human cancers, including breast carcinoma, and is associated with aggressive disease. To understand the mechanisms and vulnerabilities of MYC-driven breast cancer, we have generated an in vivo model that mimics human disease in response to MYC deregu...
Autores principales: | Lourenco, Corey, Kalkat, Manpreet, Houlahan, Kathleen E., De Melo, Jason, Longo, Joseph, Done, Susan J., Boutros, Paul C., Penn, Linda Z. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679384/ https://www.ncbi.nlm.nih.gov/pubmed/31350286 http://dx.doi.org/10.1242/dmm.038083 |
Ejemplares similares
-
MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
por: Dingar, Dharmendra, et al.
Publicado: (2018) -
MYC Deregulation in Primary Human Cancers
por: Kalkat, Manpreet, et al.
Publicado: (2017) -
BioID data of c-MYC interacting protein partners in cultured cells and xenograft tumors
por: Chan, Pak-Kei, et al.
Publicado: (2014) -
Identification of c-MYC SUMOylation by Mass Spectrometry
por: Kalkat, Manpreet, et al.
Publicado: (2014) -
Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning
por: Mergenthaler, Philipp, et al.
Publicado: (2021)