Study protocol: multicenter double-blind, randomized, placebo-controlled trial of rituximab for the treatment of childhood-onset early-stage uncomplicated frequently relapsing or steroid-dependent nephrotic syndrome (JSKDC10 trial)

BACKGROUND: Eighty percent of children with idiopathic nephrotic syndrome respond well to steroid therapy, but up to 50% of patients with steroid-sensitive nephrotic syndrome exhibit frequently relapsing (FRNS) or steroid-dependent nephrotic syndrome (SDNS). Several studies identified the chimeric a...

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Detalles Bibliográficos
Autores principales: Nagano, China, Sako, Mayumi, Kamei, Koichi, Ishikura, Kenji, Nakamura, Hidefumi, Nakanishi, Koichi, Omori, Takashi, Nozu, Kandai, Iijima, Kazumoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679488/
https://www.ncbi.nlm.nih.gov/pubmed/31375087
http://dx.doi.org/10.1186/s12882-019-1470-3

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