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The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia

Oriented cell divisions are important for the formation of normal epithelial structures. Dlg1, a tumour suppressor, is required for mitotic spindle orientation in Drosophila epithelia and chick neuroepithelia, but how Dlg1 is localised to the membrane and its importance in mammalian epithelia are un...

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Detalles Bibliográficos
Autores principales: Porter, Andrew P., White, Gavin R. M., Mack, Natalie A., Malliri, Angeliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679578/
https://www.ncbi.nlm.nih.gov/pubmed/31289196
http://dx.doi.org/10.1242/jcs.230086