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The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia
Oriented cell divisions are important for the formation of normal epithelial structures. Dlg1, a tumour suppressor, is required for mitotic spindle orientation in Drosophila epithelia and chick neuroepithelia, but how Dlg1 is localised to the membrane and its importance in mammalian epithelia are un...
Autores principales: | Porter, Andrew P., White, Gavin R. M., Mack, Natalie A., Malliri, Angeliki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679578/ https://www.ncbi.nlm.nih.gov/pubmed/31289196 http://dx.doi.org/10.1242/jcs.230086 |
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