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TGF-β family ligands exhibit distinct signalling dynamics that are driven by receptor localisation
Growth factor-induced signal transduction pathways are tightly regulated at multiple points intracellularly, but how cells monitor levels of extracellular ligand and translate this information into appropriate downstream responses remains unclear. Understanding signalling dynamics is thus a key chal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679586/ https://www.ncbi.nlm.nih.gov/pubmed/31217285 http://dx.doi.org/10.1242/jcs.234039 |