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Prevalence of medication adherence in patients with hypertension in Iran: A systematic review and meta-analysis of studies published in 2000-2018

BACKGROUND: Medication adherence (MA) has a crucial role in controlling of hypertension (HTN). A difference was observed in the prevalence of anti-hypertensive MA reported in different studies in Iran, so we aimed to determine the overall prevalence of MA. METHODS: Using the English and Persian keyw...

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Autores principales: Jafari Oori, Mehdi, Mohammadi, Farahnaz, Norouzi-Tabrizi, Kian, Fallahi-Khoshknab, Masoud, Ebadi, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679658/
https://www.ncbi.nlm.nih.gov/pubmed/31440290
http://dx.doi.org/10.22122/arya.v15i2.1807
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author Jafari Oori, Mehdi
Mohammadi, Farahnaz
Norouzi-Tabrizi, Kian
Fallahi-Khoshknab, Masoud
Ebadi, Abbas
author_facet Jafari Oori, Mehdi
Mohammadi, Farahnaz
Norouzi-Tabrizi, Kian
Fallahi-Khoshknab, Masoud
Ebadi, Abbas
author_sort Jafari Oori, Mehdi
collection PubMed
description BACKGROUND: Medication adherence (MA) has a crucial role in controlling of hypertension (HTN). A difference was observed in the prevalence of anti-hypertensive MA reported in different studies in Iran, so we aimed to determine the overall prevalence of MA. METHODS: Using the English and Persian keywords extracted from Mesh, the databases of MagIran, Barakat Knowledge Network System, Scientific Information Database (SID), Web of Sciences, PubMed, Science Direct, and Google Scholar were reviewed from 2000 to 2018. The overall prevalence of MA was estimated using Random effect mode. The I2 and Egger’s tests were used to assess heterogeneity and publication bias, respectively. Meta-regression and subgroup analysis were conducted based on variables such as age, marital status, regions, and tools. RESULTS: The overall prevalence of MA was 33%. Moreover, the prevalence of MA based on the 8-Item Morisky Medication Adherence Scale (MMAS-8), Hill-Bone Medication Adherence (HBMA) scale, researcher-made tools, and self-care tools, were 13%, 34%, 48%, and 47%, respectively. A higher MA prevalence (38%) was observed among older adults compared to other age groups, and married patients (32%) compared to single (23%) individuals. The highest MA prevalence (50%) was related to region 5 of the country. Meta-regression results showed a significant relationship between the used tools and MA prevalence. CONCLUSION: The overall prevalence of MA is low in Iran. Furthermore, MA was measured using different questionnaires, such as standard international scales and researcher-made tools. It is proposed that a standard international questionnaire should be used in future studies.
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spelling pubmed-66796582019-08-22 Prevalence of medication adherence in patients with hypertension in Iran: A systematic review and meta-analysis of studies published in 2000-2018 Jafari Oori, Mehdi Mohammadi, Farahnaz Norouzi-Tabrizi, Kian Fallahi-Khoshknab, Masoud Ebadi, Abbas ARYA Atheroscler Meta-Analysis BACKGROUND: Medication adherence (MA) has a crucial role in controlling of hypertension (HTN). A difference was observed in the prevalence of anti-hypertensive MA reported in different studies in Iran, so we aimed to determine the overall prevalence of MA. METHODS: Using the English and Persian keywords extracted from Mesh, the databases of MagIran, Barakat Knowledge Network System, Scientific Information Database (SID), Web of Sciences, PubMed, Science Direct, and Google Scholar were reviewed from 2000 to 2018. The overall prevalence of MA was estimated using Random effect mode. The I2 and Egger’s tests were used to assess heterogeneity and publication bias, respectively. Meta-regression and subgroup analysis were conducted based on variables such as age, marital status, regions, and tools. RESULTS: The overall prevalence of MA was 33%. Moreover, the prevalence of MA based on the 8-Item Morisky Medication Adherence Scale (MMAS-8), Hill-Bone Medication Adherence (HBMA) scale, researcher-made tools, and self-care tools, were 13%, 34%, 48%, and 47%, respectively. A higher MA prevalence (38%) was observed among older adults compared to other age groups, and married patients (32%) compared to single (23%) individuals. The highest MA prevalence (50%) was related to region 5 of the country. Meta-regression results showed a significant relationship between the used tools and MA prevalence. CONCLUSION: The overall prevalence of MA is low in Iran. Furthermore, MA was measured using different questionnaires, such as standard international scales and researcher-made tools. It is proposed that a standard international questionnaire should be used in future studies. Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences 2019-03 /pmc/articles/PMC6679658/ /pubmed/31440290 http://dx.doi.org/10.22122/arya.v15i2.1807 Text en © 2019 Isfahan Cardiovascular Research Center & Isfahan University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Meta-Analysis
Jafari Oori, Mehdi
Mohammadi, Farahnaz
Norouzi-Tabrizi, Kian
Fallahi-Khoshknab, Masoud
Ebadi, Abbas
Prevalence of medication adherence in patients with hypertension in Iran: A systematic review and meta-analysis of studies published in 2000-2018
title Prevalence of medication adherence in patients with hypertension in Iran: A systematic review and meta-analysis of studies published in 2000-2018
title_full Prevalence of medication adherence in patients with hypertension in Iran: A systematic review and meta-analysis of studies published in 2000-2018
title_fullStr Prevalence of medication adherence in patients with hypertension in Iran: A systematic review and meta-analysis of studies published in 2000-2018
title_full_unstemmed Prevalence of medication adherence in patients with hypertension in Iran: A systematic review and meta-analysis of studies published in 2000-2018
title_short Prevalence of medication adherence in patients with hypertension in Iran: A systematic review and meta-analysis of studies published in 2000-2018
title_sort prevalence of medication adherence in patients with hypertension in iran: a systematic review and meta-analysis of studies published in 2000-2018
topic Meta-Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679658/
https://www.ncbi.nlm.nih.gov/pubmed/31440290
http://dx.doi.org/10.22122/arya.v15i2.1807
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