Oleuropein-Induced Apoptosis Is Mediated by Mitochondrial Glyoxalase 2 in NSCLC A549 Cells: A Mechanistic Inside and a Possible Novel Nonenzymatic Role for an Ancient Enzyme

Oleuropein (OP) is a bioactive compound derived from plants of the genus Oleaceae exhibiting antitumor properties in several human cancers, including non-small-cell lung cancer (NSCLC). Recent evidence suggests that OP has proapoptotic effects on NSCLC cells via the mitochondrial apoptotic pathway....

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Detalles Bibliográficos
Autores principales: Antognelli, Cinzia, Frosini, Roberta, Santolla, Maria F., Peirce, Matthew J., Talesa, Vincenzo N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679873/
https://www.ncbi.nlm.nih.gov/pubmed/31428230
http://dx.doi.org/10.1155/2019/8576961

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