A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism

The CNS plays a pivotal role in energy homeostasis, but whether oligodendrocytes are involved has been largely unexplored. Here, we show that signaling through GPR17, a G-protein-coupled receptor predominantly expressed in the oligodendrocyte lineage, regulates food intake by modulating hypothalamic...

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Detalles Bibliográficos
Autores principales: Ou, Zhimin, Ma, Yanchen, Sun, Yuxia, Zheng, Gege, Wang, Shiyun, Xing, Rui, Chen, Xiang, Han, Ying, Wang, Jiajia, Lu, Q. Richard, Zhao, Tong-Jin, Chen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679936/
https://www.ncbi.nlm.nih.gov/pubmed/30865888
http://dx.doi.org/10.1016/j.celrep.2019.02.060

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