Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function

Regulatory T cells (Tregs) are pivotal for immune suppression. Cellular metabolism is important for Treg homeostasis and function. However, the exact role of mitochondrial respiration in Tregs remains elusive. Mitochondrial transcription factor A (Tfam) is essential for mitochondrial respiration and...

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Detalles Bibliográficos
Autores principales: Fu, Zheng, Ye, Jian, Dean, Joseph W., Bostick, John W., Weinberg, Samuel E., Xiong, Lifeng, Oliff, Kristen N., Chen, Zongming E., Avram, Dorina, Chandel, Navdeep S., Zhou, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679941/
https://www.ncbi.nlm.nih.gov/pubmed/31269437
http://dx.doi.org/10.1016/j.celrep.2019.06.024

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