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Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors
Subepithelial tumors are divided into benign subepithelial and potentially malignant gastrointestinal stromal tumors. It is difficult to distinguish between these tumor types. Contrast-enhanced harmonic endoscopic ultrasound is reportedly useful for diagnosing subepithelial tumors, can be safely and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Gastrointestinal Endoscopy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680002/ https://www.ncbi.nlm.nih.gov/pubmed/31331161 http://dx.doi.org/10.5946/ce.2019.056 |
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author | Tamura, Takashi Kitano, Masayuki |
author_facet | Tamura, Takashi Kitano, Masayuki |
author_sort | Tamura, Takashi |
collection | PubMed |
description | Subepithelial tumors are divided into benign subepithelial and potentially malignant gastrointestinal stromal tumors. It is difficult to distinguish between these tumor types. Contrast-enhanced harmonic endoscopic ultrasound is reportedly useful for diagnosing subepithelial tumors, can be safely and easily performed by understanding the principle and method, and can be used to distinguish between tumor types with high sensitivity on the basis of differences in contrast effect. The generated image shows a hyper-enhancement pattern in gastrointestinal stromal tumors (sensitivity, 78%–100%; specificity, 60%–100%; accuracy, 60%–100%) and hypo-enhancement pattern in benign subepithelial tumors. Contrast-enhanced harmonic endoscopic ultrasound can be used to estimate the malignancy potential of gastrointestinal stromal tumors by evaluating the uniformity of the contrast and the blood vessels inside the tumor, with abnormal intra-tumor blood vessels, heterogeneous enhancement, and non-enhancing spots suggesting malignancy. Contrast-enhanced harmonic endoscopic ultrasound has a higher sensitivity than other imaging modalities for the detection of vascularity within gastrointestinal stromal tumors. Additionally, it has been reported that treatment effects can be estimated by evaluating the blood flow in the gastrointestinal stromal tumor before and after treatment with tyrosine kinase inhibitors using contrast-enhanced ultrasound. However, there will be subjective-bias and the results depends on the performer’s skill. |
format | Online Article Text |
id | pubmed-6680002 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Society of Gastrointestinal Endoscopy |
record_format | MEDLINE/PubMed |
spelling | pubmed-66800022019-08-05 Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors Tamura, Takashi Kitano, Masayuki Clin Endosc Focused Review Series: Recent Update of Endoscopic Ultrasonography in Gastrointestinal Subepithelial Tumors Subepithelial tumors are divided into benign subepithelial and potentially malignant gastrointestinal stromal tumors. It is difficult to distinguish between these tumor types. Contrast-enhanced harmonic endoscopic ultrasound is reportedly useful for diagnosing subepithelial tumors, can be safely and easily performed by understanding the principle and method, and can be used to distinguish between tumor types with high sensitivity on the basis of differences in contrast effect. The generated image shows a hyper-enhancement pattern in gastrointestinal stromal tumors (sensitivity, 78%–100%; specificity, 60%–100%; accuracy, 60%–100%) and hypo-enhancement pattern in benign subepithelial tumors. Contrast-enhanced harmonic endoscopic ultrasound can be used to estimate the malignancy potential of gastrointestinal stromal tumors by evaluating the uniformity of the contrast and the blood vessels inside the tumor, with abnormal intra-tumor blood vessels, heterogeneous enhancement, and non-enhancing spots suggesting malignancy. Contrast-enhanced harmonic endoscopic ultrasound has a higher sensitivity than other imaging modalities for the detection of vascularity within gastrointestinal stromal tumors. Additionally, it has been reported that treatment effects can be estimated by evaluating the blood flow in the gastrointestinal stromal tumor before and after treatment with tyrosine kinase inhibitors using contrast-enhanced ultrasound. However, there will be subjective-bias and the results depends on the performer’s skill. Korean Society of Gastrointestinal Endoscopy 2019-07 2019-07-23 /pmc/articles/PMC6680002/ /pubmed/31331161 http://dx.doi.org/10.5946/ce.2019.056 Text en Copyright © 2019 Korean Society of Gastrointestinal Endoscopy This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Focused Review Series: Recent Update of Endoscopic Ultrasonography in Gastrointestinal Subepithelial Tumors Tamura, Takashi Kitano, Masayuki Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors |
title | Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors |
title_full | Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors |
title_fullStr | Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors |
title_full_unstemmed | Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors |
title_short | Contrast Enhanced Endoscopic Ultrasound Imaging for Gastrointestinal Subepithelial Tumors |
title_sort | contrast enhanced endoscopic ultrasound imaging for gastrointestinal subepithelial tumors |
topic | Focused Review Series: Recent Update of Endoscopic Ultrasonography in Gastrointestinal Subepithelial Tumors |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680002/ https://www.ncbi.nlm.nih.gov/pubmed/31331161 http://dx.doi.org/10.5946/ce.2019.056 |
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