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Modelling and in vitro testing of the HIV-1 Nef fitness landscape

An effective vaccine is urgently required to curb the HIV-1 epidemic. We have previously described an approach to model the fitness landscape of several HIV-1 proteins, and have validated the results against experimental and clinical data. The fitness landscape may be used to identify mutation patte...

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Detalles Bibliográficos
Autores principales:	Barton, John P, Rajkoomar, Erasha, Mann, Jaclyn K, Murakowski, Dariusz K, Toyoda, Mako, Mahiti, Macdonald, Mwimanzi, Phillip, Ueno, Takamasa, Chakraborty, Arup K, Ndung’u, Thumbi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680064/ https://www.ncbi.nlm.nih.gov/pubmed/31392033 http://dx.doi.org/10.1093/ve/vez029

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