Surface Trafficking of APP and BACE in Live Cells

Amyloid‐β (Aβ)‐peptide, the major constituent of the plaques that develop during Alzheimer's disease, is generated via the cleavage of Aβ precursor protein (APP) by β‐site APP‐cleaving enzyme (BACE). Using live‐cell imaging of APP and BACE labeled with pH‐sensitive proteins, we could detect the...

Descripción completa

Detalles Bibliográficos
Autores principales: Bauereiss, Anna, Welzel, Oliver, Jung, Jasmin, Grosse‐Holz, Simon, Lelental, Natalia, Lewczuk, Piotr, Wenzel, Eva M., Kornhuber, Johannes, Groemer, Teja W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680167/
https://www.ncbi.nlm.nih.gov/pubmed/25712587
http://dx.doi.org/10.1111/tra.12270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680167/
https://www.ncbi.nlm.nih.gov/pubmed/25712587
http://dx.doi.org/10.1111/tra.12270

Ejemplares similares