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Systems medicine in colorectal cancer: from a mathematical model toward a new type of clinical trial
Current colorectal cancer (CRC) treatment guidelines are primarily based on clinical features, such as cancer stage and grade. However, outcomes may be improved using molecular treatment guidelines. Potentially useful biomarkers include driver mutations and somatically inherited alterations, signali...
Autores principales: | Castagnino, Nicoletta, Maffei, Massimo, Tortolina, Lorenzo, Zoppoli, Gabriele, Piras, Daniela, Nencioni, Alessio, Moran, Eva, Ballestrero, Alberto, Patrone, Franco, Parodi, Silvio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680205/ https://www.ncbi.nlm.nih.gov/pubmed/27240214 http://dx.doi.org/10.1002/wsbm.1342 |
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