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Nonsense‐mediated mRNA decay: novel mechanistic insights and biological impact
Nonsense‐mediated mRNA decay (NMD) was originally coined to define a quality control mechanism that targets mRNAs with truncated open reading frames due to the presence of a premature termination codon. Meanwhile, it became clear that NMD has a much broader impact on gene expression and additional b...
Autores principales: | Karousis, Evangelos D., Nasif, Sofia, Mühlemann, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680220/ https://www.ncbi.nlm.nih.gov/pubmed/27173476 http://dx.doi.org/10.1002/wrna.1357 |
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