Vector synthesis high‐resolution electrocardiography, atrial natriuretic peptide and N‐terminal prohormone brain natriuretic peptide for estimation of cardiac load in pregnancy

AIM: We analyzed atrial natriuretic peptide (ANP), N‐terminal pro‐brain natriuretic natriuretic peptide (NT‐proBNP) and vector synthesis high‐resolution electrocardiography (ECG), to estimate cardiac load with circulatory dynamic change from pregnancy through the post‐partum period. METHODS: The subjects were singleton pregnant women (n = 19), who were divided into three stages: stage 1, 34–36 weeks of gestation; stage 2, 2–6 post‐partum days; and stage 3, 1–3 months after delivery. Vector synthesis high‐resolution ECG, ANP and NT‐proBNP were analyzed for all subjects. RESULTS: A pregnant woman with massive uterin liomyoma expressed largest the corrected recover time (RTc) dispersion in I + II of tow Dimensional (2D) color distribution map ANP and NT‐proBNP were significantly higher in stage 2 than in stages 1 and 3. CONCLUSIONS: ANP, NT‐proBNP and vector synthesis high‐resolution ECG there might be able to evaluate cardiac load of normal pregnancy.