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Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing

Rationale: There is poor understanding about protective immunity and the pathogenesis of cavitation in patients with tuberculosis. Objectives: To map pathophysiological pathways at anatomically distinct positions within the human tuberculosis cavity. Methods: Biopsies were obtained from eight predet...

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Detalles Bibliográficos
Autores principales: Dheda, Keertan, Lenders, Laura, Srivastava, Shashikant, Magombedze, Gesham, Wainwright, Helen, Raj, Prithvi, Bush, Stephen J., Pollara, Gabriele, Steyn, Rachelle, Davids, Malika, Pooran, Anil, Pennel, Timothy, Linegar, Anthony, McNerney, Ruth, Moodley, Loven, Pasipanodya, Jotam G., Turner, Carolin T., Noursadeghi, Mahdad, Warren, Robin M., Wakeland, Edward, Gumbo, Tawanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680310/
https://www.ncbi.nlm.nih.gov/pubmed/30694692
http://dx.doi.org/10.1164/rccm.201807-1361OC

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