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Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing
Rationale: There is poor understanding about protective immunity and the pathogenesis of cavitation in patients with tuberculosis. Objectives: To map pathophysiological pathways at anatomically distinct positions within the human tuberculosis cavity. Methods: Biopsies were obtained from eight predet...
Autores principales: | Dheda, Keertan, Lenders, Laura, Srivastava, Shashikant, Magombedze, Gesham, Wainwright, Helen, Raj, Prithvi, Bush, Stephen J., Pollara, Gabriele, Steyn, Rachelle, Davids, Malika, Pooran, Anil, Pennel, Timothy, Linegar, Anthony, McNerney, Ruth, Moodley, Loven, Pasipanodya, Jotam G., Turner, Carolin T., Noursadeghi, Mahdad, Warren, Robin M., Wakeland, Edward, Gumbo, Tawanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Thoracic Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680310/ https://www.ncbi.nlm.nih.gov/pubmed/30694692 http://dx.doi.org/10.1164/rccm.201807-1361OC |
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