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The Role of Orientation of Surface Bound Dihydropyrrol-2-ones (DHP) on Biological Activity

Quorum sensing (QS) signaling system is important for bacterial growth, adhesion, and biofilm formation resulting in numerous infectious diseases. Dihydropyrrol-2-ones (DHPs) represent a novel class of antimicrobial agents that inhibit QS, and are less prone to develop bacterial resistance due to th...

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Detalles Bibliográficos
Autores principales: Taunk, Aditi, Chen, Renxun, Iskander, George, Ho, Kitty K. K., Almohaywi, Basmah, Black, David StClair, Willcox, Mark D. P., Kumar, Naresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680537/
https://www.ncbi.nlm.nih.gov/pubmed/31340597
http://dx.doi.org/10.3390/molecules24142676